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切尔诺贝利灾难污染地区移民到以色列后的慢性病与死亡率:一项随访研究。

Chronic diseases and mortality among immigrants to Israel from areas contaminated by the Chernobyl disaster: a follow-up study.

作者信息

Slusky Danna A, Cwikel Julie, Quastel Michael R

机构信息

Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.

The Center for Women's Health Studies and Promotion, Ben Gurion University of the Negev, Beer Sheva, Israel.

出版信息

Int J Public Health. 2017 May;62(4):463-469. doi: 10.1007/s00038-017-0941-1. Epub 2017 Jan 27.

Abstract

OBJECTIVES

To examine six chronic diseases and all-cause mortality among immigrants to Israel from areas contaminated by the Chernobyl accident.

METHODS

The medical data were obtained from the two largest HMOs in Israel. In the assessment of chronic diseases, individuals were divided into three groups: less exposed (n = 480), more exposed (n = 359), and liquidators (n = 45) and in the mortality analysis, into two groups: less exposed (n = 792) and more exposed (n = 590).

RESULTS

Compared to the less exposed, adults from the more exposed group had increased odds of respiratory disorders (OR = 2.34, 95% CI 1.21, 4.54) and elevated odds, with borderline significance, of ischemic heart disease (OR = 2.01, 95% CI 0.97, 4.20). In addition, the liquidators had increased odds of hypertension compared to the less exposed (OR = 2.64, 95% CI 1.24, 5.64). The Cox proportional-hazards model indicated no difference in the ratio of all-cause mortality between the exposed groups during the follow up period.

CONCLUSIONS

Our study, conducted approximately two decades after the accident, suggests that exposure to radionuclides may be associated with increased odds of respiratory disorders and hypertension.

摘要

目的

研究切尔诺贝利事故污染地区的以色列移民中的六种慢性病及全因死亡率。

方法

医疗数据来自以色列两家最大的健康维护组织。在慢性病评估中,个体被分为三组:低暴露组(n = 480)、高暴露组(n = 359)和清理人员组(n = 45);在死亡率分析中,分为两组:低暴露组(n = 792)和高暴露组(n = 590)。

结果

与低暴露组相比,高暴露组的成年人患呼吸系统疾病的几率增加(比值比[OR]=2.34,95%置信区间[CI] 1.21, 4.54),患缺血性心脏病的几率增加且具有临界显著性(OR = 2.01,95% CI 0.97, 4.20)。此外,与低暴露组相比,清理人员患高血压的几率增加(OR = 2.64,95% CI 1.24, 5.64)。Cox比例风险模型表明,在随访期间,暴露组之间的全因死亡率比值无差异。

结论

我们在事故发生约二十年后进行的研究表明,接触放射性核素可能与呼吸系统疾病和高血压几率增加有关。

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