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通过3D打印对主动脉瘤和主动脉夹层进行建模。

Modelling of aortic aneurysm and aortic dissection through 3D printing.

作者信息

Ho Daniel, Squelch Andrew, Sun Zhonghua

机构信息

Department of Medical Radiation Sciences, Curtin University, Perth, Western Australia, Australia.

Department of Exploration Geophysics, Western Australian School of Mines, Curtin University, Perth, Western Australia, Australia.

出版信息

J Med Radiat Sci. 2017 Mar;64(1):10-17. doi: 10.1002/jmrs.212. Epub 2017 Jan 30.

Abstract

INTRODUCTION

The aim of this study was to assess if the complex anatomy of aortic aneurysm and aortic dissection can be accurately reproduced from a contrast-enhanced computed tomography (CT) scan into a three-dimensional (3D) printed model.

METHODS

Contrast-enhanced cardiac CT scans from two patients were post-processed and produced as 3D printed thoracic aorta models of aortic aneurysm and aortic dissection. The transverse diameter was measured at five anatomical landmarks for both models, compared across three stages: the original contrast-enhanced CT images, the stereolithography (STL) format computerised model prepared for 3D printing and the contrast-enhanced CT of the 3D printed model. For the model with aortic dissection, measurements of the true and false lumen were taken and compared at two points on the descending aorta.

RESULTS

Three-dimensional printed models were generated with strong and flexible plastic material with successful replication of anatomical details of aortic structures and pathologies. The mean difference in transverse vessel diameter between the contrast-enhanced CT images before and after 3D printing was 1.0 and 1.2 mm, for the first and second models respectively (standard deviation: 1.0 mm and 0.9 mm). Additionally, for the second model, the mean luminal diameter difference between the 3D printed model and CT images was 0.5 mm.

CONCLUSION

Encouraging results were achieved with regards to reproducing 3D models depicting aortic aneurysm and aortic dissection. Variances in vessel diameter measurement outside a standard deviation of 1 mm tolerance indicate further work is required into the assessment and accuracy of 3D model reproduction.

摘要

引言

本研究的目的是评估主动脉瘤和主动脉夹层的复杂解剖结构能否从增强计算机断层扫描(CT)扫描准确复制到三维(3D)打印模型中。

方法

对两名患者的增强心脏CT扫描进行后处理,并制作成主动脉瘤和主动脉夹层的3D打印胸主动脉模型。在两个模型的五个解剖标志点测量横径,并在三个阶段进行比较:原始增强CT图像、为3D打印准备的立体光刻(STL)格式计算机模型以及3D打印模型的增强CT。对于主动脉夹层模型,在降主动脉的两个点测量真腔和假腔,并进行比较。

结果

使用坚固且柔韧的塑料材料生成了3D打印模型,成功复制了主动脉结构和病变的解剖细节。第一个和第二个模型在3D打印前后增强CT图像之间的血管横径平均差异分别为1.0毫米和1.2毫米(标准差:1.0毫米和0.9毫米)。此外,对于第二个模型,3D打印模型与CT图像之间的管腔直径平均差异为0.5毫米。

结论

在复制描绘主动脉瘤和主动脉夹层的3D模型方面取得了令人鼓舞的结果。血管直径测量的差异在1毫米公差标准差之外,表明需要进一步开展关于3D模型复制评估和准确性的工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f14/5355365/15bd90aa6968/JMRS-64-10-g001.jpg

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