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增材制造技术在体外心血管模型生物工程中的系统分析。

A Systematic Analysis of Additive Manufacturing Techniques in the Bioengineering of In Vitro Cardiovascular Models.

机构信息

Fresenius Medical Care North America, Concord, CA, 94520, USA.

Computational Fluid Dynamics (CFD) Lab, Mechanical and Aerospace Engineering, University of Texas Arlington, Arlington, TX, 76010, USA.

出版信息

Ann Biomed Eng. 2023 Nov;51(11):2365-2383. doi: 10.1007/s10439-023-03322-x. Epub 2023 Jul 19.

Abstract

Additive Manufacturing is noted for ease of product customization and short production run cost-effectiveness. As our global population approaches 8 billion, additive manufacturing has a future in maintaining and improving average human life expectancy for the same reasons that it has advantaged general manufacturing. In recent years, additive manufacturing has been applied to tissue engineering, regenerative medicine, and drug delivery. Additive Manufacturing combined with tissue engineering and biocompatibility studies offers future opportunities for various complex cardiovascular implants and surgeries. This paper is a comprehensive overview of current technological advancements in additive manufacturing with potential for cardiovascular application. The current limitations and prospects of the technology for cardiovascular applications are explored and evaluated.

摘要

增材制造以产品定制的便利性和小批量生产的成本效益而著称。随着全球人口接近 80 亿,增材制造在维持和提高人类平均预期寿命方面具有未来的发展前景,其原因与它为一般制造业带来的优势相同。近年来,增材制造已应用于组织工程、再生医学和药物输送领域。增材制造与组织工程和生物相容性研究相结合,为各种复杂的心血管植入物和手术提供了未来的机会。本文全面概述了增材制造的当前技术进步,以及其在心血管应用方面的潜力。探讨和评估了该技术在心血管应用中的当前局限性和前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea2/10598155/33b84e6ff7e3/10439_2023_3322_Fig1_HTML.jpg

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