在一名奥地利患者的多重耐药性大肠杆菌分离株中检测该基因。
Detection of the Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient.
作者信息
Hartl Rainer, Kerschner Heidrun, Lepuschitz Sarah, Ruppitsch Werner, Allerberger Franz, Apfalter Petra
机构信息
Institute of Hygiene, Microbiology and Tropical Medicine, National Reference Centre for Nosocomial Infections and Antimicrobial Resistance, Ordensklinikum Linz - Elisabethinen, Linz, Austria.
AGES - Austrian Agency for Health and Food Safety, Institute of Medical Microbiology and Hygiene, Vienna, Austria.
出版信息
Antimicrob Agents Chemother. 2017 Mar 24;61(4). doi: 10.1128/AAC.02623-16. Print 2017 Apr.
Abstract
Since colistin resistance based on the plasmid-encoded gene was first described, this resistance gene in has been found worldwide. These organisms are typically of heterogeneous genetic background and show exceptional clonal diversity. We describe the first confirmation of in a human strain cultured from a surveillance stool sample of an Austrian oncology patient.
摘要
自从基于质粒编码基因的黏菌素耐药性首次被描述以来，这种耐药基因已在全球范围内被发现。这些微生物通常具有异质的遗传背景，并表现出异常的克隆多样性。我们描述了从一名奥地利肿瘤患者的监测粪便样本中培养出的一株人类菌株中首次证实存在该耐药基因。
相似文献
1
Detection of the Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient.在一名奥地利患者的多重耐药性大肠杆菌分离株中检测该基因。
Antimicrob Agents Chemother. 2017 Mar 24;61(4). doi: 10.1128/AAC.02623-16. Print 2017 Apr.
2
Co-occurrence of colistin-resistance genes mcr-1 and mcr-3 among multidrug-resistant Escherichia coli isolated from cattle, Spain, September 2015.2015年9月在西班牙从牛身上分离出的多重耐药性大肠杆菌中耐黏菌素基因mcr-1和mcr-3的共现情况。
Euro Surveill. 2017 Aug 3;22(31). doi: 10.2807/1560-7917.ES.2017.22.31.30586.
3
Plasmid-Mediated Colistin Resistance Gene mcr-1 in an Escherichia coli ST10 Bloodstream Isolate in the Sultanate of Oman.阿曼苏丹国一株大肠杆菌ST10血流分离株中质粒介导的黏菌素耐药基因mcr-1
Microb Drug Resist. 2018 Apr;24(3):278-282. doi: 10.1089/mdr.2017.0131. Epub 2017 Aug 11.
4
Spread of colistin resistance gene mcr-1 in Italy: characterization of the mcr-1.2 allelic variant in a colistin-resistant blood isolate of Escherichia coli.黏菌素耐药基因mcr-1在意大利的传播：一株耐黏菌素大肠杆菌血源分离株中mcr-1.2等位基因变体的特征分析
Diagn Microbiol Infect Dis. 2018 May;91(1):66-68. doi: 10.1016/j.diagmicrobio.2017.12.015. Epub 2017 Dec 24.
5
[First report in Chile of a clinical isolate of Escherichia coli resistant to colistin harbouring the mcr-1 gene].[智利首次报告携带mcr-1基因的耐黏菌素大肠埃希菌临床分离株]
Rev Chilena Infectol. 2018 Aug;35(4):453-454. doi: 10.4067/s0716-10182018000400453.
6
Co-occurrence of mcr-1 in the chromosome and on an IncHI2 plasmid: persistence of colistin resistance in Escherichia coli.mcr-1 基因同时存在于染色体和 IncHI2 型质粒上：大肠杆菌中黏菌素耐药性的持续存在。
Int J Antimicrob Agents. 2018 Jun;51(6):842-847. doi: 10.1016/j.ijantimicag.2018.01.007. Epub 2018 Jan 31.
7
Prevalence of mcr-1 in commensal Escherichia coli from French livestock, 2007 to 2014.2007 年至 2014 年法国家畜肠道共生大肠杆菌中 mcr-1 的流行情况。
Euro Surveill. 2016;21(6). doi: 10.2807/1560-7917.ES.2016.21.6.30135.
8
9
First Report of the Globally Disseminated IncX4 Plasmid Carrying the mcr-1 Gene in a Colistin-Resistant Escherichia coli Sequence Type 101 Isolate from a Human Infection in Brazil.巴西一株携带mcr-1基因的全球传播IncX4质粒在耐黏菌素大肠埃希菌序列型101分离株中的首次报告，该分离株来自人类感染。
Antimicrob Agents Chemother. 2016 Sep 23;60(10):6415-7. doi: 10.1128/AAC.01325-16. Print 2016 Oct.
10
Detection and genetic features of MCR-1-producing plasmid in human Escherichia coli infection in South Korea.韩国人类大肠杆菌感染中产MCR-1质粒的检测及遗传特征
Diagn Microbiol Infect Dis. 2017 Oct;89(2):158-160. doi: 10.1016/j.diagmicrobio.2017.06.020. Epub 2017 Jul 2.
引用本文的文献
1
Performance evaluation of a novel MBT LipidART module (Bruker Daltonics) for detection of colistin resistance in Escherichia coli and Klebsiella pneumoniae.一种用于检测大肠杆菌和肺炎克雷伯菌中黏菌素耐药性的新型MBT LipidART模块（布鲁克道尔顿公司）的性能评估
Eur J Clin Microbiol Infect Dis. 2025 Mar 12. doi: 10.1007/s10096-025-05099-4.
2
Potential sources and characteristic occurrence of mobile colistin resistance () gene-harbouring bacteria recovered from the poultry sector: a literature synthesis specific to high-income countries.从家禽部门回收的携带可移动黏菌素耐药性（）基因的细菌的潜在来源和特征性出现情况：针对高收入国家的文献综述
PeerJ. 2021 Oct 5;9:e11606. doi: 10.7717/peerj.11606. eCollection 2021.
3
The Pheno- and Genotypic Characterization of Porcine Isolates.猪分离株的表型和基因型特征
Microorganisms. 2021 Aug 6;9(8):1676. doi: 10.3390/microorganisms9081676.
4
Evaluation of two rapid phenotypical tests-Alifax rapid AST colistin test and Rapid Polymyxin NP test-for detection of colistin resistance in Enterobacterales.评价两种快速表型检测方法——Alifax 快速 AST 黏菌素检测法和 Rapid Polymyxin NP 检测法——用于检测肠杆菌科对黏菌素的耐药性。
Eur J Clin Microbiol Infect Dis. 2021 Aug;40(8):1749-1753. doi: 10.1007/s10096-021-04182-w. Epub 2021 Feb 17.
5
Molecular mechanisms of colistin resistance in Africa: A systematic review of literature.非洲黏菌素耐药性的分子机制：文献系统综述
Germs. 2020 Dec 28;10(4):367-379. doi: 10.18683/germs.2020.1229. eCollection 2020 Dec.
6
Global Burden of Colistin-Resistant Bacteria: Mobilized Colistin Resistance Genes Study (1980-2018).耐黏菌素细菌的全球负担：可移动黏菌素耐药基因研究（1980 - 2018年）
Microorganisms. 2019 Oct 16;7(10):461. doi: 10.3390/microorganisms7100461.
7
Occurrence and Characterization of -Positive Isolated From Food-Producing Animals in Poland, 2011-2016.2011 - 2016年波兰从食用动物中分离出的阳性菌的发生情况及特征
Front Microbiol. 2019 Aug 8;10:1753. doi: 10.3389/fmicb.2019.01753. eCollection 2019.
8
The rise and spread of plasmid-mediated polymyxin resistance.质粒介导的多粘菌素耐药性的出现和传播。
Crit Rev Microbiol. 2019 Mar;45(2):131-161. doi: 10.1080/1040841X.2018.1492902. Epub 2019 May 23.
9
First detection of the colistin resistance gene in from a patient with urinary tract infection in Myanmar.首次在缅甸一名尿路感染患者身上检测到耐黏菌素基因。
New Microbes New Infect. 2019 Apr 10;30:100550. doi: 10.1016/j.nmni.2019.100550. eCollection 2019 Jul.
本文引用的文献
1
Molecular mechanisms of polymyxin resistance: knowns and unknowns.多粘菌素耐药的分子机制：已知和未知。
Int J Antimicrob Agents. 2016 Dec;48(6):583-591. doi: 10.1016/j.ijantimicag.2016.06.023. Epub 2016 Aug 4.
2
Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016.2016 年 6 月，在比利时的大肠杆菌中发现了一种新型质粒介导的粘菌素耐药基因 mcr-2。
Euro Surveill. 2016 Jul 7;21(27). doi: 10.2807/1560-7917.ES.2016.21.27.30280.
3
Full-Length Nucleotide Sequences of mcr-1-Harboring Plasmids Isolated from Extended-Spectrum-β-Lactamase-Producing Escherichia coli Isolates of Different Origins.从不同来源的产超广谱β-内酰胺酶大肠埃希菌分离株中获得的携带mcr-1质粒的全长核苷酸序列
Antimicrob Agents Chemother. 2016 Aug 22;60(9):5589-91. doi: 10.1128/AAC.00935-16. Print 2016 Sep.
4
Plasmid-mediated colistin resistance (mcr-1 gene): three months later, the story unfolds.质粒介导的黏菌素耐药性（mcr-1基因）：三个月后，情况逐渐明朗。
Euro Surveill. 2016;21(9):30155. doi: 10.2807/1560-7917.ES.2016.21.9.30155.
5
Colistin resistance gene mcr-1 in extended-spectrum β-lactamase-producing and carbapenemase-producing Gram-negative bacteria in Germany.德国产超广谱β-内酰胺酶和碳青霉烯酶的革兰氏阴性菌中的黏菌素耐药基因mcr-1
Lancet Infect Dis. 2016 Mar;16(3):282-3. doi: 10.1016/S1473-3099(16)00009-8. Epub 2016 Jan 8.
6
Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study.中国动物和人类中出现的质粒介导的粘菌素耐药机制 MCR-1：微生物学和分子生物学研究。
Lancet Infect Dis. 2016 Feb;16(2):161-8. doi: 10.1016/S1473-3099(15)00424-7. Epub 2015 Nov 19.
7
Rapid and Easy In Silico Serotyping of Escherichia coli Isolates by Use of Whole-Genome Sequencing Data.利用全基因组测序数据对大肠杆菌分离株进行快速简便的电子血清分型
J Clin Microbiol. 2015 Aug;53(8):2410-26. doi: 10.1128/JCM.00008-15. Epub 2015 May 13.
8
In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing.使用质粒查找工具（PlasmidFinder）和质粒多位点序列分型进行质粒的电子检测和分型
Antimicrob Agents Chemother. 2014 Jul;58(7):3895-903. doi: 10.1128/AAC.02412-14. Epub 2014 Apr 28.
9
Identification of acquired antimicrobial resistance genes.获得性抗菌耐药基因的鉴定。
J Antimicrob Chemother. 2012 Nov;67(11):2640-4. doi: 10.1093/jac/dks261. Epub 2012 Jul 10.
10
Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance.耐多药、广泛耐药和全耐药细菌：获得性耐药的国际专家临时标准定义建议
Clin Microbiol Infect. 2012 Mar;18(3):268-81. doi: 10.1111/j.1469-0691.2011.03570.x. Epub 2011 Jul 27.
Zotero 插件