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xMAP技术：在病原体检测中的应用

xMAP Technology: Applications in Detection of Pathogens.

作者信息

Reslova Nikol, Michna Veronika, Kasny Martin, Mikel Pavel, Kralik Petr

机构信息

Department of Food and Feed Safety, Veterinary Research InstituteBrno, Czechia; Department of Botany and Zoology, Faculty of Science, Masaryk UniversityBrno, Czechia.

Department of Food and Feed Safety, Veterinary Research InstituteBrno, Czechia; Department of Experimental Biology, Faculty of Science, Masaryk UniversityBrno, Czechia.

出版信息

Front Microbiol. 2017 Jan 25;8:55. doi: 10.3389/fmicb.2017.00055. eCollection 2017.

DOI:10.3389/fmicb.2017.00055
PMID:28179899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5263158/
Abstract

xMAP technology is applicable for high-throughput, multiplex and simultaneous detection of different analytes within a single complex sample. xMAP multiplex assays are currently available in various nucleic acid and immunoassay formats, enabling simultaneous detection and typing of pathogenic viruses, bacteria, parasites and fungi and also antigen or antibody interception. As an open architecture platform, the xMAP technology is beneficial to end users and therefore it is used in various pharmaceutical, clinical and research laboratories. The main aim of this review is to summarize the latest findings and applications in the field of pathogen detection using microsphere-based multiplex assays.

摘要

xMAP技术适用于在单个复杂样本中对不同分析物进行高通量、多重和同时检测。xMAP多重检测目前有多种核酸和免疫分析形式，能够同时检测和分型致病病毒、细菌、寄生虫和真菌，还能进行抗原或抗体拦截。作为一个开放架构平台，xMAP技术对终端用户有益，因此它被用于各种制药、临床和研究实验室。本综述的主要目的是总结基于微球的多重检测在病原体检测领域的最新发现和应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/c188709255cd/fmicb-08-00055-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/787067e87b5a/fmicb-08-00055-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/ab1acd778460/fmicb-08-00055-g002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/bb9a089d149d/fmicb-08-00055-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/4729584efd9e/fmicb-08-00055-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/6275f54fdc8b/fmicb-08-00055-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/b52a956afb6b/fmicb-08-00055-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/661c0327341f/fmicb-08-00055-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/c188709255cd/fmicb-08-00055-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/787067e87b5a/fmicb-08-00055-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/ab1acd778460/fmicb-08-00055-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/527610f4684a/fmicb-08-00055-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/bb9a089d149d/fmicb-08-00055-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/4729584efd9e/fmicb-08-00055-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/6275f54fdc8b/fmicb-08-00055-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/b52a956afb6b/fmicb-08-00055-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/661c0327341f/fmicb-08-00055-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/5263158/c188709255cd/fmicb-08-00055-g009.jpg

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