用于量子点干细胞成像的磁性纳米颗粒TMADM的转导功能
Transduction Function of a Magnetic Nanoparticle TMADM for Stem-Cell Imaging with Quantum Dots.
作者信息
Ogihara Yusuke, Yukawa Hiroshi, Onoshima Daisuke, Baba Yoshinobu
机构信息
Department of Applied Chemistry, Graduate School of Engineering, Nagoya University.
出版信息
Anal Sci. 2017;33(2):143-146. doi: 10.2116/analsci.33.143.
We investigated the transduction function of a cationic dextran hydroxypropyltrimethyl ammonium chloride-coated magnetic iron oxide nanoparticle (TMADM-03) for transducing quantum dots (QDs) into adipose tissue-derived stem cells (ASCs). As a result, the fluorescence intensity of ASCs labeled with QDs using TMADM-03 was much higher than that of QDs only labeling. These data suggest that TMADM-03 can be useful as a transduction agent for QDs in stem-cell imaging.
我们研究了一种阳离子葡聚糖羟丙基三甲基氯化铵包被的磁性氧化铁纳米颗粒（TMADM-03）将量子点（QD）转导至脂肪组织来源干细胞（ASC）中的转导功能。结果，使用TMADM-03标记量子点的ASC的荧光强度远高于仅用量子点标记的荧光强度。这些数据表明，TMADM-03可作为干细胞成像中量子点的转导剂。
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