DNA damage responses in central nervous system and age-associated neurodegeneration.
作者信息
Hegde Muralidhar L, Bohr Vilhelm A, Mitra Sankar
机构信息
Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX 77030, USA; Houston Methodist Neurological Institute, Houston, TX 77030, USA; Weill Medical College of Cornell University, New York, USA.
Laboratory of Molecular Gerontology, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
出版信息
Mech Ageing Dev. 2017 Jan;161(Pt A):1-3. doi: 10.1016/j.mad.2017.01.010.
Abstract
摘要
相似文献
1
DNA damage responses in central nervous system and age-associated neurodegeneration.中枢神经系统中的DNA损伤反应与年龄相关的神经退行性变
Mech Ageing Dev. 2017 Jan;161(Pt A):1-3. doi: 10.1016/j.mad.2017.01.010.
2
Foreword: neurodegenerative diseases: challenges and opportunities.前言：神经退行性疾病：挑战与机遇
Future Med Chem. 2012 Sep;4(13):1647-9. doi: 10.4155/fmc.12.123.
3
Ferrosenescence: The iron age of neurodegeneration?铁沉积：神经退行性变的铁时代？
Mech Ageing Dev. 2018 Sep;174:63-75. doi: 10.1016/j.mad.2017.11.012. Epub 2017 Nov 24.
4
Taurine and central nervous system disorders.牛磺酸与中枢神经系统紊乱。
Amino Acids. 2014 Jan;46(1):31-46. doi: 10.1007/s00726-012-1382-z. Epub 2012 Aug 19.
5
DAMPs and neurodegeneration.损伤相关分子模式与神经退行性变。
Ageing Res Rev. 2015 Nov;24(Pt A):17-28. doi: 10.1016/j.arr.2014.11.003. Epub 2014 Nov 24.
6
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.疾病相关小胶质细胞：神经退行性变的普遍免疫传感器。
Cell. 2018 May 17;173(5):1073-1081. doi: 10.1016/j.cell.2018.05.003.
7
The Role of Lipid Bodies in the Microglial Aging Process and Related Diseases.脂滴在小胶质细胞衰老过程及相关疾病中的作用
Neurochem Res. 2017 Nov;42(11):3140-3148. doi: 10.1007/s11064-017-2351-4. Epub 2017 Jul 11.
8
Selenium, selenoproteins and neurodegenerative diseases.硒、硒蛋白与神经退行性疾病
Metallomics. 2015 Aug;7(8):1213-28. doi: 10.1039/c5mt00075k.
9
Pathogenic role of ganglioside metabolism in neurodegenerative diseases.神经节苷脂代谢在神经退行性疾病中的致病作用。
J Neurosci Res. 2014 Oct;92(10):1227-42. doi: 10.1002/jnr.23411. Epub 2014 Jun 5.
10
Oxidative RNA damage and neurodegeneration.氧化RNA损伤与神经退行性变。
Curr Med Chem. 2007;14(28):2968-75. doi: 10.2174/092986707782794078.
引用本文的文献
1
Poly (ADP-ribose) polymerases as PET imaging targets for central nervous system diseases.聚（ADP-核糖）聚合酶作为中枢神经系统疾病的正电子发射断层显像（PET）成像靶点
Front Med (Lausanne). 2022 Nov 10;9:1062432. doi: 10.3389/fmed.2022.1062432. eCollection 2022.
2
Transcriptome Sequencing Reveals Tgf-β-Mediated Noncoding RNA Regulatory Mechanisms Involved in DNA Damage in the 661W Photoreceptor Cell Line.转录组测序揭示 TGF-β 介导的非编码 RNA 调控机制在 661W 光感受器细胞系 DNA 损伤中的作用。
Genes (Basel). 2022 Nov 17;13(11):2140. doi: 10.3390/genes13112140.
3
R-loop Mediated DNA Damage and Impaired DNA Repair in Spinal Muscular Atrophy.R环介导的脊髓性肌萎缩症中的DNA损伤与DNA修复受损
Front Cell Neurosci. 2022 Jun 16;16:826608. doi: 10.3389/fncel.2022.826608. eCollection 2022.
4
Spatiotemporal 7q11.23 protein network analysis implicates the role of DNA repair pathway during human brain development.时空 7q11.23 蛋白网络分析提示 DNA 修复途径在人类大脑发育过程中的作用。
Sci Rep. 2021 Apr 15;11(1):8246. doi: 10.1038/s41598-021-87632-x.
5
Mitophagy and DNA damage signaling in human aging.人衰老过程中的自噬和 DNA 损伤信号通路
Mech Ageing Dev. 2020 Mar;186:111207. doi: 10.1016/j.mad.2020.111207. Epub 2020 Jan 7.
6
DNA damage response and repair pathway modulation by non-histone protein methylation: implications in neurodegeneration.非组蛋白甲基化对DNA损伤反应和修复途径的调控：对神经退行性变的影响
J Cell Commun Signal. 2020 Mar;14(1):31-45. doi: 10.1007/s12079-019-00538-2. Epub 2019 Nov 20.
7
RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration.RAD6B在神经元DNA损伤反应以抵抗神经退行性变过程中起关键作用。
Front Cell Neurosci. 2019 Aug 23;13:392. doi: 10.3389/fncel.2019.00392. eCollection 2019.
8
Repairing the Brain: Gene Therapy.修复大脑：基因治疗。
J Parkinsons Dis. 2018;8(s1):S123-S130. doi: 10.3233/JPD-181485.
9
DNA plasticity and damage in amyotrophic lateral sclerosis.肌萎缩侧索硬化症中的DNA可塑性与损伤
Neural Regen Res. 2018 Feb;13(2):173-180. doi: 10.4103/1673-5374.226377.
本文引用的文献
1
Nuclear DNA damage signalling to mitochondria in ageing.衰老过程中细胞核DNA损伤向线粒体的信号传导。
Nat Rev Mol Cell Biol. 2016 May;17(5):308-21. doi: 10.1038/nrm.2016.14. Epub 2016 Mar 9.
2
Genomic integrity and the ageing brain.基因组完整性与衰老大脑。
Nat Rev Neurosci. 2015 Nov;16(11):672-84. doi: 10.1038/nrn4020. Epub 2015 Oct 14.
3
Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β.生理脑活动导致神经元中的 DNA 双链断裂，淀粉样β蛋白加剧了这种情况。
Nat Neurosci. 2013 May;16(5):613-21. doi: 10.1038/nn.3356. Epub 2013 Mar 24.
4
Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases.氧化基因组损伤及其修复：在衰老和神经退行性疾病中的意义。
Mech Ageing Dev. 2012 Apr;133(4):157-68. doi: 10.1016/j.mad.2012.01.005. Epub 2012 Jan 31.
5
Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.年龄相关性神经元退行性变：核苷酸切除修复和转录偶联修复在预防神经病理学中的互补作用。
PLoS Genet. 2011 Dec;7(12):e1002405. doi: 10.1371/journal.pgen.1002405. Epub 2011 Dec 8.
6
DNA repair deficiency and neurological disease.DNA修复缺陷与神经疾病。
Nat Rev Neurosci. 2009 Feb;10(2):100-12. doi: 10.1038/nrn2559. Epub 2009 Jan 15.
7
Single-strand break repair and genetic disease.单链断裂修复与遗传疾病。
Nat Rev Genet. 2008 Aug;9(8):619-31. doi: 10.1038/nrg2380.
8
Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment.患有阿尔茨海默病和遗忘型轻度认知障碍的个体大脑中DNA碱基切除修复功能缺陷。
Nucleic Acids Res. 2007;35(16):5545-55. doi: 10.1093/nar/gkm605. Epub 2007 Aug 17.
9
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.一种新的早衰样综合征表明，基因毒性应激会抑制生长激素轴。
Nature. 2006 Dec 21;444(7122):1038-43. doi: 10.1038/nature05456.
10
The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates.神经退行性疾病蛋白共济失调性毛细血管扩张症突变蛋白可解决流产性DNA连接中间体问题。
Nature. 2006 Oct 12;443(7112):713-6. doi: 10.1038/nature05164. Epub 2006 Sep 10.
Zotero 插件