Nielsen Julie Bøjstrup, Kyvsgaard Julie Nyholm, Sildorf Stine Møller, Kreiner Svend, Svensson Jannet
Copenhagen Diabetes Research Center (CPH-DIRECT), Department of Paediatrics, Herlev University Hospital, Herlev Ringvej 75, Herlev, 2730, Denmark.
Section of Biostatistics, Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade 5, Copenhagen K, 1014, Denmark.
Health Qual Life Outcomes. 2017 Mar 1;15(1):44. doi: 10.1186/s12955-017-0618-8.
Type 1 Diabetes (T1D) has a negative impact on psychological and overall well-being. Screening for Health-related Quality of Life (HrQoL) and addressing HrQoL issues in the clinic leads to improved well-being and metabolic outcomes. The aim of this study was to translate the generic and diabetes-specific validated multinational DISABKIDS® questionnaires into Danish, and then determine their validity and reliability.
The questionnaires were translated using a validated translation procedure and completed by 99 children and adolescents from our diabetes-department; all diagnosed with T1D and were aged between 8 and 18 years old. The Rasch and the graphical log linear Rasch model (GLLRM) were used to determine validity. Monte Carlo methods and Cronbach's α were used to confirm reliability.
The data did not fit a pure Rasch model but did fit a GLLRM when item six in the independence scale is excluded. The six subscales measure different aspects of HrQoL indicating that all the subscales are necessary. The questionnaire shows local dependency between items and differential item functioning (DIF). Therefore age, gender, and glycated hemoglobin (HbA1c) levels must be taken into account when comparing HrQoL between groups.
The Danish versions of the DISABKIDS® chronic-generic and diabetes-specific modules provide valid and objective measurements with adequate reliability. These Danish versions are useful tools for evaluating HrQoL in Danish patients with T1D. However, guidelines on how to manage DIF and local independence will be required, and item six should be rephrased.
1型糖尿病(T1D)对心理和整体幸福感有负面影响。筛查健康相关生活质量(HrQoL)并在临床中解决HrQoL问题可改善幸福感和代谢结果。本研究的目的是将经过验证的通用型和糖尿病特异性跨国DISABKIDS®问卷翻译成丹麦语,然后确定其有效性和可靠性。
问卷采用经过验证的翻译程序进行翻译,由我们糖尿病科的99名儿童和青少年完成;所有患者均被诊断为T1D,年龄在8至18岁之间。使用拉施模型和图形对数线性拉施模型(GLLRM)来确定有效性。采用蒙特卡罗方法和克朗巴哈α系数来确认可靠性。
数据不符合纯拉施模型,但在排除独立性量表中的第6项后符合GLLRM。六个子量表测量了HrQoL的不同方面,表明所有子量表都是必要的。问卷显示项目之间存在局部依赖性和项目功能差异(DIF)。因此,在比较不同组之间的HrQoL时,必须考虑年龄、性别和糖化血红蛋白(HbA1c)水平。
DISABKIDS®慢性通用型和糖尿病特异性模块的丹麦语版本提供了具有足够可靠性的有效和客观测量。这些丹麦语版本是评估丹麦T1D患者HrQoL的有用工具。然而,需要有关如何处理DIF和局部独立性的指南,并且第6项应重新措辞。