Hu Xiaoyi, Jiang Jiaojiao, Wang Haozhong, Zhang Lei, Dong Birong, Yang Ming
The Center of Gerontology and Geriatrics The Center of Rehabilitation The Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Medicine (Baltimore). 2017 Mar;96(10):e6268. doi: 10.1097/MD.0000000000006268.
Both sleep disorders and sarcopenia are common among older adults. However, little is known about the relationship between these 2 conditions.This study aimed to investigate the possible association between sleep duration and sarcopenia in a population of Chinese community-dwelling older adults.Community-dwelling older adults aged 60 years or older were recruited. Self-reported sleep duration, anthropometric data, gait speed, and handgrip strength were collected by face-to-face interviews. Sarcopenia was defined according to the recommended algorithm of the Asian Working Group for Sarcopenia (AWGS).We included 607 participants aged 70.6 ± 6.6 years (range, 60-90 years) in the analyses. The prevalence of sarcopenia in the whole study population was 18.5%. In women, the prevalence of sarcopenia was significantly higher in the short sleep duration group (< 6 hours) and long sleep duration group (>8 hours) compared with women in the normal sleep duration group (6-8 hours; 27.5%, 22.2% and 13.9%, respectively; P = .014). Similar results were found in men; however, the differences between groups were not statistically significant (18.5%, 20.6%, and 13.0%, respectively; P = .356). After adjustments for the potential confounding factors, older women having short sleep duration (OR: 4.34; 95% CI: 1.74-10.85) or having long sleep duration (OR: 2.50; 95% CI: 1.05-6.99) had greater risk of sarcopenia compared with women having normal sleep duration. With comparison to men with normal sleep duration, the adjusted OR for sarcopenia was 2.12 (0.96-8.39) in the short sleep duration group and 2.25 (0.88-6.87) in the long sleep duration group, respectively.A U-shape relationship between self-reported sleep duration and sarcopenia was identified in a population of Chinese community-dwelling older adults, especially in women.
睡眠障碍和肌肉减少症在老年人中都很常见。然而,这两种情况之间的关系却鲜为人知。本研究旨在调查中国社区居住老年人中睡眠时间与肌肉减少症之间可能存在的关联。招募了60岁及以上的社区居住老年人。通过面对面访谈收集自我报告的睡眠时间、人体测量数据、步速和握力。肌肉减少症根据亚洲肌肉减少症工作组(AWGS)推荐的算法进行定义。我们纳入了607名年龄在70.6±6.6岁(范围为60-90岁)的参与者进行分析。整个研究人群中肌肉减少症的患病率为18.5%。在女性中,与正常睡眠时间组(6-8小时)的女性相比,短睡眠时间组(<6小时)和长睡眠时间组(>8小时)的肌肉减少症患病率显著更高(分别为27.5%、22.2%和13.9%;P=0.014)。在男性中也发现了类似的结果;然而,组间差异无统计学意义(分别为18.5%、20.6%和13.0%;P=0.356)。在对潜在混杂因素进行调整后,与睡眠时间正常的女性相比,睡眠时间短(OR:4.34;95%CI:1.74-10.85)或睡眠时间长(OR:2.50;95%CI:1.05-6.99)的老年女性患肌肉减少症的风险更高。与睡眠时间正常的男性相比,短睡眠时间组和长睡眠时间组肌肉减少症的调整后OR分别为2.12(0.96-8.39)和2.25(0.88-6.87)。在中国社区居住老年人中,尤其是女性中,自我报告的睡眠时间与肌肉减少症之间存在U型关系。