Baker Jessica H, Peterson Claire M, Thornton Laura M, Brownley Kimberly A, Bulik Cynthia M, Girdler Susan S, Marcus Marsha D, Bromberger Joyce T
Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Eur Eat Disord Rev. 2017 May;25(3):188-194. doi: 10.1002/erv.2510. Epub 2017 Mar 9.
Eating disorders and related symptoms occur during midlife; however, little is known about their aetiology. It has been hypothesised that perimenopause represents a window of vulnerability for the development or exacerbation of eating disorder symptomatology because, like puberty, perimenopause is a period of reproductive hormone change. We compared symptoms of bulimia nervosa (bulimic symptomatology) assessed via mean scores on a self-report questionnaire in premenopausal and perimenopausal women. We also examined the association between hormone concentrations (reproductive/appetite) and bulimic symptomatology. No mean differences in bulimic symptomatology were observed between premenopause and perimenopause. However, there was a significant positive association between leptin and binge eating. Although no significant associations between reproductive hormones and bulimic symptomatology were observed, additional research is needed to provide definitive information. It is essential to learn more about the aetiology of eating disorders and related symptomatology across the lifespan in order to develop age-relevant treatment and prevention programs. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.
饮食失调及相关症状在中年期出现；然而，人们对其病因知之甚少。有假设认为，围绝经期是饮食失调症状发展或加重的一个易损期，因为与青春期一样，围绝经期是生殖激素发生变化的时期。我们比较了通过自我报告问卷的平均得分评估的绝经前和围绝经期女性的神经性贪食症症状（贪食症状）。我们还研究了激素浓度（生殖激素/食欲相关激素）与贪食症状之间的关联。绝经前和围绝经期之间未观察到贪食症状的平均差异。然而，瘦素与暴饮暴食之间存在显著的正相关。虽然未观察到生殖激素与贪食症状之间存在显著关联，但仍需要进一步研究以提供确切信息。为了制定与年龄相关的治疗和预防方案，有必要更多地了解饮食失调及相关症状在整个生命周期中的病因。版权所有© 2017约翰·威利父子有限公司和饮食失调协会。
