Alenazy Ali B, Wells R Glenn, Ruddy Terrence D
a Department of Medicine , University of Ottawa , Ottawa , Canada.
b Division of Cardiology , University of Ottawa Heart Institute , Ottawa , Canada.
Expert Rev Med Devices. 2017 Mar;14(3):213-222. doi: 10.1080/17434440.2017.1296763. Epub 2017 Mar 1.
Single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is well established as diagnostic test for patients with suspected or known coronary artery disease. New camera systems have been developed with cadmium-zinc-telluride (CZT) detectors, novel collimator designs and reconstruction software. Areas covered: We review the current state of cardiac SPECT, advances in conventional camera technology and the development and clinical validation of solid-state CZT cameras. Expert commentary: The development of CZT systems is timely and addresses current issues for clinical SPECT imaging. These systems have a significant increase in photon sensitivity, permitting much lower radiation patient doses at a time when the lay and medical communities are very concerned about the radiation doses resulting from medical imaging. The increased count sensitivity permits shorter acquisition times and greater patient throughput which may address the ongoing and increasing issue of decreased funding for healthcare and, particularly, diagnostic imaging. The improved image resolution should improve diagnostic accuracy and increase the value of SPECT imaging for management of patients with CAD at a time of significant competition from other imaging modalities.
单光子发射计算机断层扫描（SPECT）心肌灌注成像（MPI）作为疑似或已知冠状动脉疾病患者的诊断测试已得到广泛认可。新型相机系统已采用碲化镉锌（CZT）探测器、新颖的准直器设计和重建软件进行开发。涵盖领域：我们回顾了心脏SPECT的当前状态、传统相机技术的进展以及固态CZT相机的开发和临床验证。专家评论：CZT系统的开发恰逢其时，解决了临床SPECT成像的当前问题。这些系统的光子灵敏度显著提高，在普通民众和医学界非常关注医学成像辐射剂量之际，能够使患者接受的辐射剂量大大降低。计数灵敏度的提高允许缩短采集时间并提高患者通量，这可能解决医疗保健资金持续减少以及特别是诊断成像资金减少这一日益严重的问题。在与其他成像方式竞争激烈的情况下，改进后的图像分辨率应能提高诊断准确性并增加SPECT成像在冠心病患者管理中的价值。
