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本文引用的文献

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Determinants of antipsychotic response in schizophrenia: implications for practice and future clinical trials.精神分裂症中抗精神病药物反应的决定因素：对实践和未来临床试验的启示。
J Clin Psychiatry. 2014 Apr;75(4):e308-16. doi: 10.4088/JCP.13m08853.
2
DSM and the death of phenomenology in america: an example of unintended consequences.《精神疾病诊断与统计手册》与美国现象学的式微：一个意外后果的例证
Schizophr Bull. 2007 Jan;33(1):108-12. doi: 10.1093/schbul/sbl054. Epub 2006 Dec 7.
3
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia.抗精神病药物对慢性精神分裂症患者的疗效。
N Engl J Med. 2005 Sep 22;353(12):1209-23. doi: 10.1056/NEJMoa051688. Epub 2005 Sep 19.
4
The positive and negative syndrome scale (PANSS) for schizophrenia.精神分裂症的阳性与阴性症状量表（PANSS）
Schizophr Bull. 1987;13(2):261-76. doi: 10.1093/schbul/13.2.261.

一致性检验可提高阳性与阴性症状量表（PANSS）的测量效果。

Consistency checks to improve measurement with the Positive and Negative Syndrome Scale (PANSS).

机构信息

Bar Ilan University, Ramat Gan, Israel.

SUNY Downstate Medical Center, Brooklyn, NY, USA.

出版信息

Schizophr Res. 2017 Dec;190:74-76. doi: 10.1016/j.schres.2017.03.017. Epub 2017 Mar 9.

DOI:10.1016/j.schres.2017.03.017
PMID:28285023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5662474/
Abstract

International Society for CNS Clinical Trials and Methodology convened an expert working-group that assembled consistency/inconsistency flags for the Positive and Negative Syndrome Scale (PANSS). Twenty-four flags were identified and divided based on extent to which they represent error (Possibly, Probably, Very probably or definitely). The flags were applied to assessments derived from the NEWMEDS data repository and the CATIE clinical trial data. Almost 40% of ratings had at least one inconsistency flag raised and 10% had two. Application of flags to clinical rating can improve reliability and validity of trials.

摘要

国际中枢神经系统临床试验和方法学学会召集了一个专家工作组，为阳性和阴性综合征量表 (PANSS) 制定了一致性/不一致性标志。确定了 24 个标志，并根据它们代表错误的程度（可能、很可能、非常可能或肯定）进行了划分。这些标志应用于从 NEWMEDS 数据存储库和 CATIE 临床试验数据中得出的评估。几乎 40%的评分至少有一个不一致标志被提出，10%有两个。标志的应用可以提高临床试验的可靠性和有效性。