Centre for Applied Molecular Biology, 87 West Canal Bank Road, Thokar Niaz Baig, University of the Punjab, Lahore, Pakistan.
Centre for Applied Molecular Biology, 87 West Canal Bank Road, Thokar Niaz Baig, University of the Punjab, Lahore, Pakistan; Vice Chancellor Hazara University, Mansehra, Pakistan.
Int J Infect Dis. 2017 May;58:69-76. doi: 10.1016/j.ijid.2017.03.006. Epub 2017 Mar 10.
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that is emerging as a global threat because of the highly debilitating nature of the associated disease and unprecedented magnitude of its spread. Chikungunya originated in Africa and has since spread across the entire globe causing large numbers of epidemics that have infected millions of people in Asia, the Indian subcontinent, Europe, the Americas, and Pacific Islands. Phylogenetic analysis has identified four different genotypes of CHIKV: Asian, West African, East/Central/South African (ECSA), and Indian Ocean Lineage (IOL). In the absence of well-designed epidemiological studies, the aim of this review article was to summarize the global epidemiology of CHIKV and to provide baseline data for future research on the treatment, prevention, and control of this life-threatening disease.
基孔肯雅热病毒（CHIKV）是一种通过蚊子传播的甲病毒，由于其相关疾病的高度致残性质以及前所未有的传播规模，它正在成为一种全球威胁。基孔肯雅热最初起源于非洲，此后已蔓延至全球各地，引发了大量的流行病，感染了亚洲、印度次大陆、欧洲、美洲和太平洋岛屿上数百万人。系统发育分析确定了 CHIKV 的四个不同基因型：亚洲型、西非型、东/中非/南非型（ECSA）和印度洋谱系（IOL）。由于缺乏精心设计的流行病学研究，本文旨在总结 CHIKV 的全球流行病学，为未来针对这种危及生命的疾病的治疗、预防和控制研究提供基线数据。
