乳腺癌的形态计量分析：与生存的关联
Morphometric analysis of breast carcinoma: association with survival.
作者信息
Parham D M, Robertson A J, Brown R A
机构信息
Department of Pathology, University of Dundee, Scotland.
出版信息
J Clin Pathol. 1988 Feb;41(2):173-7. doi: 10.1136/jcp.41.2.173.
Abstract
In a retrospective study of 126 cases of infiltrating ductal adenocarcinoma of the breast the percentage area of sections of each neoplasm occupied by malignant cells was assessed by morphometry. The duration of postoperative survival was related to the area occupied by tumour cells within a neoplasm; the greater the tumour cell area to stroma the more prolonged the survival. This variable seemed to be independent of histological grade and was of greater prognostic importance than the diameter of the neoplasm. Furthermore, combination of percentage of tumour area with histological grade provided greater information on the survival characteristics of these patients. Extensive tumour necrosis was a particularly poor prognostic feature.
摘要
在一项对126例乳腺浸润性导管腺癌的回顾性研究中，通过形态计量学评估了每个肿瘤切片中恶性细胞所占的面积百分比。术后生存期与肿瘤内肿瘤细胞所占面积有关；肿瘤细胞面积与间质面积之比越大，生存期越长。这一变量似乎与组织学分级无关，并且比肿瘤直径具有更大的预后重要性。此外，肿瘤面积百分比与组织学分级相结合能提供关于这些患者生存特征的更多信息。广泛的肿瘤坏死是一个特别差的预后特征。
相似文献
1
Morphometric analysis of breast carcinoma: association with survival.乳腺癌的形态计量分析：与生存的关联
J Clin Pathol. 1988 Feb;41(2):173-7. doi: 10.1136/jcp.41.2.173.
2
[Analysis of the clinicopathological characteristics and prognosis in 674 cases of breast intraductal papillary tumor].674例乳腺导管内乳头状瘤临床病理特征及预后分析
Zhonghua Zhong Liu Za Zhi. 2017 Jun 23;39(6):429-433. doi: 10.3760/cma.j.issn.0253-3766.2017.06.006.
3
Nucleolar organizer regions: a prognostic factor in infiltrating ductal carcinoma in the breast.核仁组织区：乳腺浸润性导管癌的一个预后因素。
Pathologica. 1993 Mar-Apr;85(1096):151-62.
4
Influence of the in situ component in 389 infiltrating ductal breast carcinomas.389 例浸润性导管乳腺癌原位成分的影响。
Breast Cancer. 2013 Jul;20(3):213-7. doi: 10.1007/s12282-011-0330-1. Epub 2012 Jan 21.
5
Prognostic significance of tumour infiltrating B lymphocytes in breast ductal carcinoma in situ.乳腺导管原位癌中肿瘤浸润性B淋巴细胞的预后意义
Histopathology. 2017 Aug;71(2):258-268. doi: 10.1111/his.13217. Epub 2017 May 26.
6
Grade of ductal carcinoma in situ accompanying infiltrating ductal carcinoma as an independent prognostic factor.伴有浸润性导管癌的导管原位癌分级作为独立的预后因素。
Clin Breast Cancer. 2013 Oct;13(5):385-91. doi: 10.1016/j.clbc.2013.04.005. Epub 2013 Jul 17.
7
Nuclear morphometry and DNA flow cytometry as prognostic factors in female breast cancer.细胞核形态测定法和DNA流式细胞术作为女性乳腺癌的预后因素
Eur J Surg. 1992 Mar;158(3):135-41.
8
Stromal characteristics are adequate prognosticators for recurrence risk in ductal carcinoma in situ of the breast.间质特征是乳腺导管原位癌复发风险的良好预后预测指标。
Eur J Surg Oncol. 2019 Apr;45(4):550-559. doi: 10.1016/j.ejso.2018.11.005. Epub 2018 Nov 12.
9
Different distribution of breast cancer subtypes in breast ductal carcinoma in situ (DCIS), DCIS with microinvasion, and DCIS with invasion component.不同亚型乳腺癌在乳腺导管原位癌（DCIS）、微浸润性 DCIS 和伴有浸润成分的 DCIS 中的分布情况。
Ann Surg Oncol. 2011 May;18(5):1342-8. doi: 10.1245/s10434-010-1407-3. Epub 2010 Nov 2.
10
[Prognostic factors in breast cancer].[乳腺癌的预后因素]
Rev Med Chir Soc Med Nat Iasi. 2012 Jan-Mar;116(1):262-7.
引用本文的文献
1
HuR is a post-transcriptional regulator of core metabolic enzymes in pancreatic cancer.HuR 是胰腺癌核心代谢酶的转录后调节因子。
RNA Biol. 2013 Aug;10(8):1312-23. doi: 10.4161/rna.25274. Epub 2013 Jun 13.
2
Modelling the growth of solid tumours and incorporating a method for their classification using nonlinear elasticity theory.利用非线性弹性理论对实体肿瘤的生长进行建模并纳入一种对其进行分类的方法。
J Math Biol. 1993;31(5):431-73. doi: 10.1007/BF00173886.
3
Equilibrium model of a vascularized spherical carcinoma with central necrosis--some properties of the solution.
J Math Biol. 1993;31(7):735-45. doi: 10.1007/BF00160422.
4
Quantitation of human milk fat globule (HMFG1) expression in breast carcinoma and its association with survival.人乳脂肪球（HMFG1）在乳腺癌中的表达定量及其与生存的关联。
J Clin Pathol. 1988 Aug;41(8):875-9. doi: 10.1136/jcp.41.8.875.
5
Breast carcinoma cellularity and its relation to oestrogen receptor content.乳腺癌细胞密度及其与雌激素受体含量的关系。
J Clin Pathol. 1989 Nov;42(11):1166-8. doi: 10.1136/jcp.42.11.1166.
6
Cytometric and histopathologic features of tumors detected in a randomized mammography screening program: correlation and relative prognostic influence.
Breast Cancer Res Treat. 1990 May;15(3):149-60. doi: 10.1007/BF01806352.
7
Simplified method of grading primary carcinomas of the breast.简化的乳腺癌原发性癌分级方法。
J Clin Pathol. 1992 Jun;45(6):517-20. doi: 10.1136/jcp.45.6.517.
本文引用的文献
1
2
The influence of the host and the neoplastic cell population on the collagen content of a tumor mass.宿主和肿瘤细胞群体对肿瘤块胶原含量的影响。
Cancer Res. 1963 May;23:648-53.
3
Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years.乳腺癌的组织学分级与预后；对1409例病例的研究，其中359例已随访15年。
Br J Cancer. 1957 Sep;11(3):359-77. doi: 10.1038/bjc.1957.43.
4
Prognostic value of measurement of elastosis in breast carcinoma.乳腺癌中弹性组织变性测量的预后价值
J Clin Pathol. 1981 Jul;34(7):738-43. doi: 10.1136/jcp.34.7.738.
5
Prognostic indicators in breast cancer--morphometric methods.乳腺癌的预后指标——形态测量方法。
Histopathology. 1982 May;6(3):327-39. doi: 10.1111/j.1365-2559.1982.tb02727.x.
6
A prognostic index in primary breast cancer.原发性乳腺癌的预后指数
Br J Cancer. 1982 Mar;45(3):361-6. doi: 10.1038/bjc.1982.62.
7
Intralaboratory variations in the grading of breast carcinoma.乳腺癌分级的实验室内部差异。
Arch Pathol Lab Med. 1982 Mar;106(3):126-8.
8
Oestrogen receptor assay of cryostat sections of human breast carcinomas with simultaneous quantitative histology.人乳腺癌冷冻切片雌激素受体测定及同步定量组织学分析
J Clin Pathol. 1983 Apr;36(4):399-405. doi: 10.1136/jcp.36.4.399.
9
Tumour cellularity, oestrogen receptors and prognosis in breast cancer.
Clin Oncol. 1983 Dec;9(4):311-8.
10
The pathological findings of breast cancer in patients surviving 25 years after radical mastectomy.乳腺癌根治术后存活25年患者的病理检查结果。
Cancer. 1982 Nov 15;50(10):2131-8. doi: 10.1002/1097-0142(19821115)50:10<2131::aid-cncr2820501027>3.0.co;2-a.
Zotero 插件