乳腺癌细胞密度及其与雌激素受体含量的关系。
Breast carcinoma cellularity and its relation to oestrogen receptor content.
作者信息
Parham D M, Baker P R, Robertson A J, Vasishta A, Baker P G, Smith G
机构信息
Department of Pathology, Ninewells Hospital, Dundee, Scotland.
出版信息
J Clin Pathol. 1989 Nov;42(11):1166-8. doi: 10.1136/jcp.42.11.1166.
Abstract
The cellularity of 104 primary breast carcinomata was determined by semiautomated image analysis to allow the relation between cellularity and oestrogen receptor content values to be assessed. The oestrogen receptor content of tumours detected by a steroid binding assay showed no correlation with cellularity, although a possible weak negative correlation was observed between tumour cellularity and oestrogen receptor content detected by enzyme immunoassay. It is concluded that there is no single direct correlation between tumour cellularity and oestrogen receptor content.
摘要
通过半自动图像分析确定了104例原发性乳腺癌的细胞密度，以便评估细胞密度与雌激素受体含量值之间的关系。通过类固醇结合试验检测的肿瘤雌激素受体含量与细胞密度无相关性，尽管通过酶免疫测定法检测的肿瘤细胞密度与雌激素受体含量之间观察到可能存在弱负相关。得出的结论是，肿瘤细胞密度与雌激素受体含量之间不存在单一的直接相关性。
相似文献
1
Breast carcinoma cellularity and its relation to oestrogen receptor content.乳腺癌细胞密度及其与雌激素受体含量的关系。
J Clin Pathol. 1989 Nov;42(11):1166-8. doi: 10.1136/jcp.42.11.1166.
2
Oestrogen receptors, lactate dehydrogenase and cellularity in human breast cancer.
Clin Chim Acta. 1988 Jun 30;175(1):89-96. doi: 10.1016/0009-8981(88)90038-1.
3
Oestrogen receptor content and cancer cell/stroma ratio in mammary carcinoma.乳腺癌中的雌激素受体含量与癌细胞/基质比例
APMIS. 1988 Dec;96(12):1140-2. doi: 10.1111/j.1699-0463.1988.tb00992.x.
4
Tumour cellularity, oestrogen receptors and prognosis in breast cancer.
Clin Oncol. 1983 Dec;9(4):311-8.
5
Comparison of new immunohistochemical assay for oestrogen receptor in paraffin wax embedded breast carcinoma tissue with quantitative enzyme immunoassay.石蜡包埋乳腺癌组织中雌激素受体新免疫组织化学检测法与定量酶免疫测定法的比较
J Clin Pathol. 1994 Oct;47(10):900-5. doi: 10.1136/jcp.47.10.900.
6
Oestrogen receptor assay and morphology of breast cancer.
Pathology. 1981 Apr;13(2):317-25. doi: 10.3109/00313028109081671.
7
Histopathological characteristics and oestrogen receptor content in primary breast carcinoma.原发性乳腺癌的组织病理学特征及雌激素受体含量
Virchows Arch A Pathol Anat Histol. 1981;390(3):347-51. doi: 10.1007/BF00496564.
8
Tumour epithelial cellularity and quantitative oestrogen receptor values in primary breast cancer.原发性乳腺癌中的肿瘤上皮细胞密度与雌激素受体定量值
Br J Cancer. 1983 Apr;47(4):549-52. doi: 10.1038/bjc.1983.87.
9
Oestrogen receptor assay of cryostat sections of human breast carcinomas with simultaneous quantitative histology.人乳腺癌冷冻切片雌激素受体测定及同步定量组织学分析
J Clin Pathol. 1983 Apr;36(4):399-405. doi: 10.1136/jcp.36.4.399.
10
Glucose-6-phosphate dehydrogenase activity in human breast cancer. Lack of association with oestrogen receptor content.
Acta Pathol Microbiol Scand A. 1981 Jul;89(4):263-70. doi: 10.1111/j.1699-0463.1981.tb00220.x.
引用本文的文献
1
Cellularity and oestrogen receptor content in breast cancer microsamples.乳腺癌微量样本中的细胞密度和雌激素受体含量
J Clin Pathol. 1990 Aug;43(8):698-9. doi: 10.1136/jcp.43.8.698.
本文引用的文献
1
Cellularity and the quantitation of estrogen receptors.
Breast Cancer Res Treat. 1982;2(3):239-42. doi: 10.1007/BF01806936.
2
Tumour epithelial cellularity and quantitative oestrogen receptor values in primary breast cancer.原发性乳腺癌中的肿瘤上皮细胞密度与雌激素受体定量值
Br J Cancer. 1983 Apr;47(4):549-52. doi: 10.1038/bjc.1983.87.
3
Oestradiol receptors in carcinoma and benign disease of the breast: an in vitro assay.乳腺癌及乳腺良性疾病中的雌二醇受体：一项体外检测
Br J Cancer. 1971 Dec;25(4):697-710. doi: 10.1038/bjc.1971.85.
4
Malignant and benign human mammary disease: estrogen binding in relation to clinical data.恶性和良性人类乳腺疾病：雌激素结合与临床数据的关系
Cancer. 1974 May;33(5):1364-8. doi: 10.1002/1097-0142(197405)33:5<1364::aid-cncr2820330522>3.0.co;2-7.
5
Specific estrogen-binding capacity of the cytoplasmic receptor in normal and neoplastic breast tissues of humans.人类正常和肿瘤性乳腺组织中细胞质受体的特异性雌激素结合能力。
Cancer Res. 1972 Sep;32(9):1983-92.
6
A morphometric analysis of human breast carcinoma.人类乳腺癌的形态计量分析。
Br J Cancer. 1972 Jun;26(3):234-7. doi: 10.1038/bjc.1972.32.
7
Relationship between ER-ICA and conventional steroid receptor assays in human breast cancer.
Breast Cancer Res Treat. 1986;8(1):35-43. doi: 10.1007/BF01805923.
8
Quantitation of human milk fat globule (HMFG1) expression in breast carcinoma and its association with survival.人乳脂肪球（HMFG1）在乳腺癌中的表达定量及其与生存的关联。
J Clin Pathol. 1988 Aug;41(8):875-9. doi: 10.1136/jcp.41.8.875.
9
Proteinase-like peptidase activities and oestrogen receptor levels in breast cancer tissue.乳腺癌组织中的类蛋白酶样肽酶活性和雌激素受体水平。
J Cancer Res Clin Oncol. 1989;115(1):89-92. doi: 10.1007/BF00391606.
10
Morphometric analysis of breast carcinoma: association with survival.乳腺癌的形态计量分析：与生存的关联
J Clin Pathol. 1988 Feb;41(2):173-7. doi: 10.1136/jcp.41.2.173.
Zotero 插件