Parham D M, Baker P R, Robertson A J, Vasishta A, Baker P G, Smith G
Department of Pathology, Ninewells Hospital, Dundee, Scotland.
J Clin Pathol. 1989 Nov;42(11):1166-8. doi: 10.1136/jcp.42.11.1166.
The cellularity of 104 primary breast carcinomata was determined by semiautomated image analysis to allow the relation between cellularity and oestrogen receptor content values to be assessed. The oestrogen receptor content of tumours detected by a steroid binding assay showed no correlation with cellularity, although a possible weak negative correlation was observed between tumour cellularity and oestrogen receptor content detected by enzyme immunoassay. It is concluded that there is no single direct correlation between tumour cellularity and oestrogen receptor content.
通过半自动图像分析确定了104例原发性乳腺癌的细胞密度，以便评估细胞密度与雌激素受体含量值之间的关系。通过类固醇结合试验检测的肿瘤雌激素受体含量与细胞密度无相关性，尽管通过酶免疫测定法检测的肿瘤细胞密度与雌激素受体含量之间观察到可能存在弱负相关。得出的结论是，肿瘤细胞密度与雌激素受体含量之间不存在单一的直接相关性。
