Liverani Liliana, Boccaccini Aldo R
Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Cauerstr. 6, 91058 Erlangen, Germany.
Nanomaterials (Basel). 2016 Apr 15;6(4):75. doi: 10.3390/nano6040075.
The electrospinning technique is widely used for the fabrication of micro- and nanofibrous structures. Recent studies have focused on the use of less toxic and harmful solvents (benign solvents) for electrospinning, even if those solvents usually require an accurate and longer process of optimization. The aim of the present work is to demonstrate the versatility of the use of benign solvents, like acetic acid and formic acid, for the fabrication of microfibrous and nanofibrous electrospun poly(epsilon-caprolactone) mats. The solvent systems were also shown to be suitable for the fabrication of electrospun structures with macroporosity, as well as for the fabrication of composite electrospun mats, fabricated by the addition of bioactive glass (45S5 composition) particles in the polymeric solution.
静电纺丝技术被广泛用于制备微米和纳米纤维结构。最近的研究集中在使用毒性和危害性较小的溶剂（良性溶剂）进行静电纺丝，即便这些溶剂通常需要精确且耗时更长的优化过程。本工作的目的是证明使用良性溶剂（如乙酸和甲酸）制备微米纤维和纳米纤维静电纺聚（ε-己内酯）垫材的多功能性。还表明这些溶剂体系适用于制备具有大孔隙率的静电纺结构，以及通过在聚合物溶液中添加生物活性玻璃（45S5成分）颗粒制备复合静电纺垫材。
