Chieruzzi Manila, Pagano Stefano, Moretti Silvia, Pinna Roberto, Milia Egle, Torre Luigi, Eramo Stefano
Department of Civil and Environmental Engineering-UdR INSTM-University of Perugia, Strada di Pentima, 4-05100 Terni, Italy.
Department of Surgical and Biomedical Sciences-University of Perugia, S. Andrea delle Fratte, 06156 Perugia, Italy.
Nanomaterials (Basel). 2016 Jul 21;6(7):134. doi: 10.3390/nano6070134.
The tissue engineering (TE) of dental oral tissue is facing significant changes in clinical treatments in dentistry. TE is based on a stem cell, signaling molecule, and scaffold triad that must be known and calibrated with attention to specific sectors in dentistry. This review article shows a summary of micro- and nanomorphological characteristics of dental tissues, of stem cells available in the oral region, of signaling molecules usable in TE, and of scaffolds available to guide partial or total reconstruction of hard, soft, periodontal, and bone tissues. Some scaffoldless techniques used in TE are also presented. Then actual and future roles of nanotechnologies about TE in dentistry are presented.
口腔组织工程在牙科临床治疗中正面临重大变革。组织工程基于干细胞、信号分子和支架三联体，必须了解并针对牙科的特定领域进行校准。这篇综述文章总结了牙齿组织的微观和纳米形态特征、口腔区域可用的干细胞、组织工程中可用的信号分子，以及用于指导硬组织、软组织、牙周组织和骨组织部分或全部重建的支架。还介绍了组织工程中使用的一些无支架技术。然后阐述了纳米技术在牙科组织工程中的当前和未来作用。
