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阿魏酸的结构-抗氧化活性关系

The Structure-Antioxidant Activity Relationship of Ferulates.

作者信息

Karamać Magdalena, Koleva Lidiya, Kancheva Vessela D, Amarowicz Ryszard

机构信息

Department of Chemical and Physical Properties of Food, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, 10-748 Olsztyn, Poland.

Lipid Chemistry Department, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria.

出版信息

Molecules. 2017 Mar 25;22(4):527. doi: 10.3390/molecules22040527.

DOI:10.3390/molecules22040527
PMID:28346342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6154093/
Abstract

The antioxidant activity of ferulic acid (), ferulic acid (), coniferyl aldehyde (), methyl ferulate (), and ethyl ferulate () were investigated using 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and ferric-reducing antioxidant power (FRAP) assays and autoxidation of triacylglycerols of commercially available sunflower oil (TGSO). The compounds tested for ability to scavenge ABTS radical cations was in the order of ferulic acid > coniferyl aldehyde ≈ ferulic acid > ethyl ferulate ≈ methyl ferulate. The results of the FRAP assay for ferulic acid, ferulic acid, and coniferyl aldehyde were similar to and higher than those of methyl ferulate and ethyl ferulate. In the lipid system, ferulic acid showed weak antioxidant activity. The other ferulates exhibited much stronger, yet similar, activities.

摘要

使用2,2'-联氮双(3-乙基苯并噻唑啉-6-磺酸)(ABTS)、铁还原抗氧化能力(FRAP)测定法以及市售葵花籽油三酰甘油(TGSO)的自动氧化,研究了阿魏酸()、阿魏酸()、松柏醛()、阿魏酸甲酯()和阿魏酸乙酯()的抗氧化活性。测试的化合物清除ABTS自由基阳离子的能力顺序为:阿魏酸>松柏醛≈阿魏酸>阿魏酸乙酯≈阿魏酸甲酯。阿魏酸、阿魏酸和松柏醛的FRAP测定结果与阿魏酸甲酯和阿魏酸乙酯相似且更高。在脂质体系中,阿魏酸表现出较弱的抗氧化活性。其他阿魏酸酯表现出更强但相似的活性。

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