evaluation of the antibacterial activity of five sealers used in root canal therapy.

BACKGROUND

Antibacterial activity is one of the important characteristics of an ideal root canal sealer. The aim of this study was to investigate the antibacterial activity of five different sealers against using two different methods.

MATERIALS AND METHODS

The mineral trioxide aggregate (MTA) Fillapex, Tg-sealer, Endomethasone, AH-26, and RoekoSeal sealers were placed into the brain heart infusion (BHI) culture medium containing (PTCC1393). The diameter of the bacterial zone of inhibition was measured. In the direct contact test, a suspension containing grinded set sealers and bacteria was cultured in BHI after 6, 15, and 60 min. The number of colonies in milliliter was calculated. Data were subjected to one-way ANOVA and Tukey's multiple comparisons test ( < 0.05).

RESULTS

In the agar diffusion test, Endomethasone had the highest antibacterial activity against compared to other sealers ( < 0.001). In the direct test, the antibacterial effect of MTA Fillapex was significantly higher than that of all other sealers ( < 0.001).

CONCLUSION

The technique and components of the tested sealers affect the antibacterial activity results. This study showed that all of sealers had antimicrobial effect.