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添加到不同基质根管封闭剂中的草药提取物抗菌效果评估:一项研究。

Evaluation of the Antimicrobial Efficacy of Herbal Extracts Added to Root Canal Sealers of Different Bases: An Study.

作者信息

Devi Minarani T, Saha Sonali, Tripathi Abhay M, Dhinsa Kavita, Kalra Sonali K, Ghoshal Ujjala

机构信息

Department of Pedodontics and Preventive Dentistry, Sardar Patel Postgraduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India.

Department of Applied Sciences and Biotechnology, Faculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, India.

出版信息

Int J Clin Pediatr Dent. 2019 Sep-Oct;12(5):398-404. doi: 10.5005/jp-journals-10005-1660.

Abstract

AIM

This study aimed to evaluate and compare the antimicrobial efficacy of root canal sealers of different bases when mixed with herbal extracts.

MATERIALS AND METHODS

An evaluation of three sealers (Endomethasone, AH plus, Apexit plus) mixed with three herbal extracts [ (), (Nutmeg) and (Miswak)] was done against nine strains of bacteria at various time intervals using the agar diffusion test. Moreover, measurement of the mean zones of inhibition was done.

RESULTS

The largest zones of bacterial growth inhibition were observed with Endomethasone mixed with (Nutmeg) followed in the descending order by AH plus mixed with (Miswak) and Apexit plus mixed with (Miswak) respectively. The differences between zones of inhibition among different groups were found to be statistically significant.

CONCLUSION

Zinc-oxide-eugenol-based sealer (Endomethasone) mixed with herbal extracts produced the largest inhibitory zones followed in the descending order by resin-based sealer (AH plus) and calcium-hydroxide-based sealer (Apexit plus), respectively.

CLINICAL SIGNIFICANCE

Herbal plants such as [ (), (Nutmeg) and (Miswak)] are rich sources of bioactive compounds that possess antimicrobial properties. Mixing their extracts with endodontic sealers can produce additive antimicrobial effect against microbes found in inflamed pulp.

HOW TO CITE THIS ARTICLE

Devi MT, Saha S, Tripathi AM, Evaluation of the Antimicrobial Efficacy of Herbal Extracts Added to Root Canal Sealers of Different Bases: An Study. Int J Clin Pediatr Dent 2019;12(5):398-404.

摘要

目的

本研究旨在评估和比较不同基质的根管封闭剂与草药提取物混合后的抗菌效果。

材料与方法

使用琼脂扩散试验,在不同时间间隔对三种封闭剂(Endomethasone、AH plus、Apexit plus)与三种草药提取物[()、肉豆蔻和米斯瓦克]混合后针对九种细菌菌株进行评估。此外,还测量了平均抑菌圈。

结果

观察到Endomethasone与肉豆蔻混合后的细菌生长抑制圈最大,其次依次是AH plus与米斯瓦克混合、Apexit plus与米斯瓦克混合,且不同组之间抑菌圈的差异具有统计学意义。

结论

氧化锌丁香酚类封闭剂(Endomethasone)与草药提取物混合产生的抑菌圈最大,其次依次是树脂类封闭剂(AH plus)和氢氧化钙类封闭剂(Apexit plus)。

临床意义

诸如[()、肉豆蔻和米斯瓦克]等草药富含具有抗菌特性的生物活性化合物。将它们的提取物与牙髓封闭剂混合可对发炎牙髓中的微生物产生附加抗菌作用。

如何引用本文

Devi MT, Saha S, Tripathi AM, 不同基质根管封闭剂添加草药提取物的抗菌效果评估:一项研究。《国际临床儿科牙科杂志》2019年;12(5):398 - 404。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/710c/7229369/183275702a8b/ijcpd-12-398-g001.jpg

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