Ahmed Salman, Hasan Muhammad Mohtasheemul, Mahmood Zafar Alam
Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan.
Colorcon Limited UK, Flagship House, Victory Way, Crossways, Dartford, Kent, DA26 QD-England.
Pak J Pharm Sci. 2016 Nov;29(6):2129-2139.
About 12% of world population is affected by different forms of urolithiasis in which the recurrence rate in female is 47-60% and in male is 70-80%. According to WHO 75% people rely on traditional medicines for the prevention and cure of different ailments. Similarly, the majority of the world population use a number of plants to treat problems related to the urinary tract system in which urolithiasis is the major cause. The aim of the review is to collect the data of the plants used in different parts and cultures of the world against urolithiasis with their parts, mode of preparation, dosage and administration. A literature review was conducted for traditionally used antiurolithiatic plants. The articles mentioning plant, parts, mode of preparation, dose and route of administration were selected. This information was extracted to compose Mono and Poly herbal antiurolithiatic formulations used in Appalachia (region in Eastern United States), Canada, India, Iran, Israel, Italy, Jordan, Latin America, Pakistan, Turkey and Yemen. The review provides an important data about plants used as antiurolithiatic in different parts of the world. The information not only useful for common people, but also for the scientific community to carry out further phytochemical, pharmacological and toxicological studies for the discovery of new, effective and safer molecules against urolithiasis.
世界上约12%的人口受到不同形式的尿石症影响，其中女性的复发率为47%-60%，男性为70%-80%。据世界卫生组织称，75%的人依靠传统药物来预防和治疗各种疾病。同样，世界上大多数人口使用多种植物来治疗与泌尿系统相关的问题，其中尿石症是主要原因。本综述的目的是收集世界各地不同地区和文化中用于治疗尿石症的植物的数据，包括其使用部位、制备方法、剂量和给药方式。对传统使用的抗尿石症植物进行了文献综述。选择了提及植物、部位、制备方法、剂量和给药途径的文章。提取这些信息以组成用于美国东部地区阿巴拉契亚、加拿大、印度、伊朗、以色列、意大利、约旦、拉丁美洲、巴基斯坦、土耳其和也门的单味和多味草药抗尿石症制剂。该综述提供了有关世界各地用作抗尿石症的植物的重要数据。这些信息不仅对普通人有用，而且对科学界进行进一步的植物化学、药理学和毒理学研究以发现针对尿石症的新的、有效且更安全的分子也有用。
