肺结核治疗后的肺功能受损：疾病的终结？
Impaired pulmonary function after treatment for tuberculosis: the end of the disease?
作者信息
Chushkin Mikhail Ivanovich, Ots Oleg Nikolayevich
机构信息
. Research Institute of Phthisiopulmonology, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
. Medical Center, Central Bank of Russian Federation, Moscow, Russia.
出版信息
J Bras Pneumol. 2017 Jan-Feb;43(1):38-43. doi: 10.1590/S1806-37562016000000053.
OBJECTIVE
: To evaluate the prevalence of pulmonary function abnormalities and to investigate the factors affecting lung function in patients treated for pulmonary tuberculosis.
METHODS
: A total of 214 consecutive patients (132 men and 82 women; 20-82 years of age), treated for pulmonary tuberculosis and followed at a local dispensary, underwent spirometry and plethysmography at least one year after treatment.
RESULTS
: Pulmonary impairment was present in 102 (47.7%) of the 214 patients evaluated. The most common functional alteration was obstructive lung disease (seen in 34.6%). Of the 214 patients, 60 (28.0%) showed reduced pulmonary function (FEV1 below the lower limit of normal). Risk factors for reduced pulmonary function were having had culture-positive pulmonary tuberculosis in the past, being over 50 years of age, having recurrent tuberculosis, and having a lower level of education.
CONCLUSIONS
: Nearly half of all tuberculosis patients evolve to impaired pulmonary function. That underscores the need for pulmonary function testing after the end of treatment.
OBJETIVO
: Avaliar a prevalência de alterações da função pulmonar e investigar os fatores que afetam a função pulmonar em pacientes tratados para tuberculose pulmonar.
MÉTODOS:: Um total de 214 pacientes consecutivos (132 homens e 82 mulheres; 20-82 anos de idade), tratados para tuberculose pulmonar e acompanhados em um dispensário local, foi submetido a espirometria e pletismografia pelo menos um ano após o tratamento.
RESULTADOS
: O comprometimento pulmonar estava presente em 102 (47,7%) dos 214 pacientes avaliados. A alteração funcional mais comum foi o distúrbio ventilatório obstrutivo (observado em 34,6%). Dos 214 pacientes, 60 (28,0%) apresentaram função pulmonar reduzida (VEF1 abaixo do limite inferior de normalidade). Os fatores de risco para função pulmonar reduzida foram tuberculose pulmonar com cultura positiva no passado, idade acima de 50 anos, recidiva de tuberculose e menor nível de escolaridade.
CONCLUSÕES:: Quase metade de todos os pacientes com tuberculose evolui com comprometimento da função pulmonar. Isso reforça a necessidade de testes de função pulmonar após o término do tratamento.
目的
评估肺结核治疗患者肺功能异常的患病率，并调查影响肺功能的因素。
方法
共有214例连续的肺结核治疗患者（132名男性和82名女性；年龄20 - 82岁），在当地药房接受随访，治疗后至少一年进行了肺活量测定和体积描记法检查。
结果
在214例接受评估的患者中，102例（47.7%）存在肺功能损害。最常见的功能改变是阻塞性肺疾病（见于34.6%）。在214例患者中，60例（28.0%）肺功能降低（第一秒用力呼气容积低于正常下限）。肺功能降低的危险因素包括既往有痰培养阳性的肺结核、年龄超过50岁、复发性肺结核以及受教育程度较低。
结论
几乎一半的肺结核患者会出现肺功能损害。这突出了治疗结束后进行肺功能检测的必要性。
目的
评估肺结核治疗患者肺功能改变的患病率，并调查影响肺功能的因素。
方法
共有214例连续的肺结核治疗患者（132名男性和82名女性；年龄20 - 82岁），在当地药房接受随访，治疗后至少一年进行了肺活量测定和体积描记法检查。
结果
在214例接受评估的患者中，102例（47.7%）存在肺功能损害。最常见的功能改变是阻塞性通气障碍（见于34.6%）。在214例患者中，60例（28.0%）肺功能降低（第一秒用力呼气容积低于正常下限）。肺功能降低的危险因素包括既往痰培养阳性的肺结核、年龄超过50岁、肺结核复发以及受教育程度较低。
结论
几乎一半的肺结核患者会出现肺功能损害。这进一步强调了治疗结束后进行肺功能检测的必要性。
Zotero 插件