Nayak Kashinath, Garg Aaina, Mithra Prasanna, Manjrekar Poornima
Department of Dermatology, Venereology and Leprology, Kasturba Medical College, Mangalore, Manipal University, Karnataka, India.
Undergraduate student, Kasturba Medical College, Mangalore, Manipal University, Karnataka, India.
Int J Trichology. 2016 Oct-Dec;8(4):160-164. doi: 10.4103/ijt.ijt_57_16.
Hair fall is a common problem faced by many younger people, which has variety of risk factors. Vitamin D has emerged as a molecule with key role to play in various disorders. This study was done to assess its role in diffuse hair fall among student population.
This was a case-control study including young adults presenting with complaints of hair fall (>100 a day) as cases, with age-matched healthy controls. Vitamin D levels were measured in all the patients. Data analysis was done using Statistical Package for Social Sciences version 11.5 software and significance was tested using Chi-square test and binary logistic regression analysis.
Atotal of 44 participants were enrolled; 22 in each arm. The mean age of the study population was 20.89 years (standard deviation: 1.49). The median value of Vitamin D was 6.80 (interquartile range - 5.350-16.63) for the study population. Overall, 81.8% cases had Vitamin D deficiency compared to 45.5% of controls and this difference was statistically significant ( = 0.007). Furthermore, females had a statistically significant difference in Vitamin D levels between cases and controls. Higher level of full sleeve cloth usage, sunscreen lotion application, and lesser sun exposures were seen among cases although these differences were not statistically significant. The levels of Vitamin D were not significantly different among Indians, nonresident Indians, and foreigners. None of the cases had normal Vitamin D values whereas 4.5% controls fell in the normal category.
Female patients with diffuse hair fall were found to have significantly low Vitamin D levels among student population.
脱发是许多年轻人面临的常见问题，存在多种风险因素。维生素D已成为在各种疾病中发挥关键作用的一种分子。本研究旨在评估其在学生群体弥漫性脱发中的作用。
这是一项病例对照研究，纳入有脱发主诉（每天>100根）的年轻成年人作为病例组，与年龄匹配的健康对照组。对所有患者测量维生素D水平。使用社会科学统计软件包11.5版进行数据分析，并采用卡方检验和二元逻辑回归分析检验显著性。
共招募了44名参与者；每组22名。研究人群的平均年龄为20.89岁（标准差：1.49）。研究人群的维生素D中位数为6.80（四分位间距 - 5.350 - 16.63）。总体而言，81.8%的病例存在维生素D缺乏，而对照组为45.5%，这种差异具有统计学显著性（P = 0.007）。此外，女性病例组和对照组的维生素D水平存在统计学显著差异。病例组中长袖衣物穿着、涂抹防晒霜和较少日晒的比例较高，尽管这些差异无统计学显著性。印度人、非居民印度人和外国人之间的维生素D水平无显著差异。病例组中无一例维生素D值正常，而对照组中有4.5%属于正常范围。
在学生群体中，弥漫性脱发的女性患者维生素D水平显著较低。
