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fastMitoCalc:一个用于从全基因组序列中估计线粒体DNA拷贝数的超快速程序。

fastMitoCalc: an ultra-fast program to estimate mitochondrial DNA copy number from whole-genome sequences.

作者信息

Qian Yong, Butler Thomas J, Opsahl-Ong Krista, Giroux Nicholas S, Sidore Carlo, Nagaraja Ramaiah, Cucca Francesco, Ferrucci Luigi, Abecasis Gonçalo R, Schlessinger David, Ding Jun

机构信息

Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD, USA.

Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy.

出版信息

Bioinformatics. 2017 May 1;33(9):1399-1401. doi: 10.1093/bioinformatics/btw835.

DOI:10.1093/bioinformatics/btw835
PMID:28453676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5860513/
Abstract

AVAILABILITY AND IMPLEMENTATION

fastMitoCalc is available at https://lgsun.irp.nia.nih.gov/hsgu/software/mitoAnalyzer/index.html.

CONTACT

jun.ding@nih.gov.

SUPPLEMENTARY INFORMATION

Supplementary data are available at Bioinformatics online.

摘要

可用性与实施

fastMitoCalc可在https://lgsun.irp.nia.nih.gov/hsgu/software/mitoAnalyzer/index.html获取。

联系方式

jun.ding@nih.gov。

补充信息

补充数据可在《生物信息学》在线获取。

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Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number.人类线粒体DNA拷贝数的年龄相关性和异质性相关性变异
PLoS Genet. 2016 Mar 15;12(3):e1005939. doi: 10.1371/journal.pgen.1005939. eCollection 2016 Mar.
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Genetic Control over mtDNA and Its Relationship to Major Depressive Disorder.线粒体DNA的遗传控制及其与重度抑郁症的关系。
Curr Biol. 2015 Dec 21;25(24):3170-7. doi: 10.1016/j.cub.2015.10.065. Epub 2015 Dec 10.
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Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools.使用定制测序分析工具评估约2000名撒丁岛人的淋巴细胞中的线粒体DNA变异和拷贝数。
PLoS Genet. 2015 Jul 14;11(7):e1005306. doi: 10.1371/journal.pgen.1005306. eCollection 2015 Jul.
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Molecular signatures of major depression.重度抑郁症的分子特征
Curr Biol. 2015 May 4;25(9):1146-56. doi: 10.1016/j.cub.2015.03.008. Epub 2015 Apr 23.
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Mitochondrial DNA copy number is associated with breast cancer risk.线粒体 DNA 拷贝数与乳腺癌风险相关。
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A prospective study of mitochondrial DNA copy number and risk of non-Hodgkin lymphoma.线粒体DNA拷贝数与非霍奇金淋巴瘤风险的前瞻性研究。
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