Suppr超能文献

补充不同的茶(来自茶树)可预防缺血再灌注中的记忆缺陷和海马体氧化应激。

Supplementation with different teas from Camellia sinensis prevents memory deficits and hippocampus oxidative stress in ischemia-reperfusion.

作者信息

Martins Alexandre, Schimidt Helen L, Garcia Alexandre, Colletta Altermann Caroline Dalla, Santos Francielli W, Carpes Felipe P, da Silva Weber Cláudio, Mello-Carpes Pâmela B

机构信息

Physiology Research Group, Federal University of Pampa, Uruguaiana, RS, Brazil.

Applied Neuromechanics Group, Federal University of Pampa, Uruguaiana, RS, Brazil.

出版信息

Neurochem Int. 2017 Sep;108:287-295. doi: 10.1016/j.neuint.2017.04.019. Epub 2017 Apr 29.

Abstract

Memory and cognition impairments resultant of ischemic stroke could be minimized or avoided by antioxidant supplementation. In this regard, the neuroprotective potential of Green tea from Camellia sinensis has been investigated. However, there is a lack of information regarding the neuroprotective potential of others teas processed from the Camellia sinensis. Here we investigate the neuroprotective role of green, red, white and black tea on memory deficits and brain oxidative stress in a model of ischemic stroke in rats. Our findings show that green and red teas prevent deficits in object and social recognition memories, but only green tea protects against deficits in spatial memory and avoids hippocampal oxidative status and intense necrosis and others alterations in the brain tissue. In summary, green tea shows better neuroprotection in ischemic stroke than the others teas from Camellia sinensis.

摘要

缺血性中风导致的记忆和认知障碍可通过补充抗氧化剂来最小化或避免。在这方面,已对来自茶树的绿茶的神经保护潜力进行了研究。然而,关于由茶树加工而成的其他茶的神经保护潜力,目前缺乏相关信息。在此,我们研究了绿茶、红茶、白茶和黑茶对大鼠缺血性中风模型中记忆缺陷和脑氧化应激的神经保护作用。我们的研究结果表明,绿茶和红茶可预防物体识别记忆和社交识别记忆缺陷,但只有绿茶能预防空间记忆缺陷,并避免海马体氧化状态以及脑组织中的严重坏死和其他改变。总之,在缺血性中风中,绿茶比其他来自茶树的茶表现出更好的神经保护作用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验