Morrison Michael
Centre for Health, Law and Emerging Technologies (HeLEX), Nuffield Department of Population Health, University of Oxford, Ewert House, Ewert Place, Banbury Road, Oxford, OX2 7DD, UK.
Life Sci Soc Policy. 2017 Dec;13(1):7. doi: 10.1186/s40504-017-0053-y. Epub 2017 May 4.
The rise of 'big biology' is bringing academic and industrial scientists together in large consortia to address translational challenges in the life sciences. In order to assess the impact of this change, this paper examines the existing norms and styles of collaboration in one high profile translational domain; stem cell research. Data is drawn from qualitative interviews with academic and industry scientists working in a large European stem cell research project. Respondents discussed what they perceived as the main benefits and risks of collaborative research, what styles of collaboration they were familiar with, and what collaborative work in stem cell science normally involves. A wide range of materials, data, and expertise can be exchanged during collaborative work. Informal collaborations are governed by an ethos of reciprocity and mediated by trust while formal project agreements can provide a safe space for sharing between unfamiliar partners. These characteristics make stem cell research well suited to pre-competitive public-private ventures but translation of new products to market may be more challenging.
“大生物学”的兴起正促使学术科学家和产业科学家在大型联盟中携手合作，以应对生命科学领域的转化挑战。为了评估这一变化带来的影响，本文考察了一个备受瞩目的转化领域——干细胞研究中现有的合作规范和模式。数据来源于对参与一个大型欧洲干细胞研究项目的学术科学家和产业科学家的定性访谈。受访者讨论了他们所认为的合作研究的主要益处和风险、他们熟悉的合作模式，以及干细胞科学中的合作工作通常涉及哪些方面。在合作过程中，可以交流广泛的材料、数据和专业知识。非正式合作受互惠理念的支配，并由信任介导，而正式的项目协议可为陌生伙伴之间的共享提供一个安全的空间。这些特点使得干细胞研究非常适合竞争前的公私合营企业，但将新产品推向市场可能更具挑战性。
