McCafferty Sean, Lim Garrett, Duncan William, Enikov Eniko T, Schwiegerling Jim, Levine Jason, Kew Corin
Department of Ophthalmology, College of Optical Science, University of Arizona.
Intuor Technologies.
Clin Ophthalmol. 2017 May 3;11:835-840. doi: 10.2147/OPTH.S135272. eCollection 2017.
Clinically evaluate a modified applanating surface Goldmann tonometer prism designed to substantially negate errors due to patient variability in biomechanics.
A modified Goldmann prism with a correcting applanation tonometry surface (CATS) was mathematically optimized to minimize the intraocular pressure (IOP) measurement error due to patient variability in corneal thickness, stiffness, curvature, and tear film adhesion force. A comparative clinical study of 109 eyes measured IOP with CATS and Goldmann prisms. The IOP measurement differences between the CATS and Goldmann prisms were correlated to corneal thickness, hysteresis, and curvature.
The CATS tonometer prism in correcting for Goldmann central corneal thickness (CCT) error demonstrated a reduction to <±2 mmHg in 97% of a standard CCT population. This compares to only 54% with CCT error <±2 mmHg using the Goldmann prism. Equal reductions of ~50% in errors due to corneal rigidity and curvature were also demonstrated.
The results validate the CATS prism's improved accuracy and expected reduced sensitivity to Goldmann errors without IOP bias as predicted by mathematical modeling. The CATS replacement for the Goldmann prism does not change Goldmann measurement technique or interpretation.
对一种改良的压平表面戈德曼眼压计棱镜进行临床评估,该棱镜旨在基本消除因患者生物力学差异而产生的误差。
对带有校正压平眼压测量表面(CATS)的改良戈德曼棱镜进行数学优化,以将因患者角膜厚度、硬度、曲率和泪膜粘附力差异而导致的眼压(IOP)测量误差降至最低。一项针对109只眼睛的比较临床研究使用CATS和戈德曼棱镜测量眼压。CATS和戈德曼棱镜之间的眼压测量差异与角膜厚度、滞后现象和曲率相关。
校正戈德曼中央角膜厚度(CCT)误差的CATS眼压计棱镜在97%的标准CCT人群中显示误差降低至<±2 mmHg。相比之下,使用戈德曼棱镜时,只有54%的CCT误差<±2 mmHg。在因角膜硬度和曲率导致的误差方面也显示出约50%的同等降低。
结果验证了CATS棱镜提高的准确性以及如数学模型所预测的对戈德曼误差的预期降低的敏感性,且无眼压偏差。用CATS替代戈德曼棱镜不会改变戈德曼测量技术或解读方式。