Morris Daniel O, Loeffler Anette, Davis Meghan F, Guardabassi Luca, Weese J Scott
Department of Clinical Studies - Philadelphia, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey St, Philadelphia, PA, 19104, USA.
Department of Clinical Sciences and Services, Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hertfordshire, AL9 7TA, UK.
Vet Dermatol. 2017 Jun;28(3):304-e69. doi: 10.1111/vde.12444.
Multiple drug resistance (MDR) in staphylococci, including resistance to the semi-synthetic penicillinase-resistant penicillins such as meticillin, is a problem of global proportions that presents serious challenges to the successful treatment of staphylococcal infections of companion animals.
The objective of this document is to provide harmonized recommendations for the diagnosis, prevention and treatment of meticillin-resistant staphylococcal infections in dogs and cats.
The authors served as a Guideline Panel (GP) and reviewed the literature available prior to September 2016. The GP prepared a detailed literature review and made recommendations on selected topics. The World Association of Veterinary Dermatology (WAVD) provided guidance and oversight for this process. A draft of the document was presented at the 8th World Congress of Veterinary Dermatology (May 2016) and was then made available via the World Wide Web to the member organizations of the WAVD for a period of three months. Comments were solicited and posted to the GP electronically. Responses were incorporated by the GP into the final document.
Adherence to guidelines for the diagnosis, laboratory reporting, judicious therapy (including restriction of use policies for certain antimicrobial drugs), personal hygiene, and environmental cleaning and disinfection may help to mitigate the progressive development and dissemination of MDR staphylococci.
葡萄球菌中的多重耐药性(MDR),包括对诸如甲氧西林等半合成耐青霉素酶青霉素的耐药性,是一个全球性问题,给伴侣动物葡萄球菌感染的成功治疗带来了严峻挑战。
本文档的目的是为犬猫耐甲氧西林葡萄球菌感染的诊断、预防和治疗提供统一的建议。
作者作为指南小组(GP),回顾了2016年9月之前的现有文献。指南小组进行了详细的文献综述,并就选定的主题提出了建议。世界兽医皮肤病学协会(WAVD)为这一过程提供了指导和监督。该文档的草稿在第八届世界兽医皮肤病学大会(2016年5月)上进行了展示,随后通过万维网向WAVD的成员组织提供了三个月。征求了意见并以电子方式发送给指南小组。指南小组将回复纳入最终文档。
遵守诊断、实验室报告、合理治疗(包括限制某些抗菌药物的使用政策)、个人卫生以及环境清洁和消毒等指南,可能有助于减轻耐多药葡萄球菌的逐步发展和传播。