2014年日本人类轮状病毒G8P[8] 暴发株的临床和分子特征
Clinical and Molecular Characteristics of Human Rotavirus G8P[8] Outbreak Strain, Japan, 2014.
作者信息
Kondo Kenji, Tsugawa Takeshi, Ono Mayumi, Ohara Toshio, Fujibayashi Shinsuke, Tahara Yasuo, Kubo Noriaki, Nakata Shuji, Higashidate Yoshihito, Fujii Yoshiki, Katayama Kazuhiko, Yoto Yuko, Tsutsumi Hiroyuki
出版信息
Emerg Infect Dis. 2017 Jun;23(6):968-972. doi: 10.3201/eid2306.160038.
During March-July 2014, rotavirus G8P[8] emerged as the predominant cause of rotavirus gastroenteritis among children in Hokkaido Prefecture, Japan. Clinical characteristics were similar for infections caused by G8 and non-G8 strains. Sequence and phylogenetic analyses suggest the strains were generated by multiple reassortment events between DS-1-like P[8] strains and bovine strains from Asia.
2014年3月至7月期间，轮状病毒G8P[8]成为日本北海道地区儿童轮状病毒肠胃炎的主要病因。G8毒株和非G8毒株引起的感染临床特征相似。序列和系统发育分析表明，这些毒株是由DS-1样P[8]毒株与来自亚洲的牛毒株之间的多次重配事件产生的。
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