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在泌尿生殖医学诊所就诊的男同性恋者中进行细胞学筛查，以检测亚临床肛门人乳头瘤病毒（HPV）感染。

Cytological screening to detect subclinical anal human papillomavirus (HPV) infection in homosexual men attending genitourinary medicine clinic.

作者信息

Haye K R, Maiti H, Stanbridge C M

机构信息

Department of Genitourinary Medicine, Royal Infirmary, Manchester.

出版信息

Genitourin Med. 1988 Dec;64(6):378-82. doi: 10.1136/sti.64.6.378.

DOI:10.1136/sti.64.6.378
PMID:2852158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1194271/
Abstract

Unselected homosexual men attending a department of genitourinary medicine were screened for human papilloma virus (HPV) infection using anal cytology. Satisfactory smears were obtained from 221 patients, and 73 showed cytological abnormality with warty atypia. Abnormal cytology was detected in 55 (31%) of 178 patients in whom there was no macroscopic evidence of anal or perianal warts, and anal cytology may therefore be valuable to detect patients with subclinical condylomatous lesions and may also serve to identify those who possibly have intraepithelial neoplasia.

摘要

在一家泌尿生殖医学科就诊的未经过挑选的男同性恋者接受了肛门细胞学检查，以筛查人乳头瘤病毒（HPV）感染情况。从221例患者中获得了满意的涂片，其中73例显示有湿疣样异型性的细胞学异常。在178例肛门或肛周无肉眼可见疣体的患者中，55例（31%）检测到细胞学异常，因此肛门细胞学检查对于检测亚临床湿疣样病变患者可能有价值，也可用于识别可能患有上皮内瘤变的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c680/1194271/756fe33fd708/genitmed00060-0022-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c680/1194271/a14259f9ed23/genitmed00060-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c680/1194271/ae8dd3cd551f/genitmed00060-0021-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c680/1194271/4654a3201e86/genitmed00060-0022-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c680/1194271/756fe33fd708/genitmed00060-0022-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c680/1194271/a14259f9ed23/genitmed00060-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c680/1194271/ae8dd3cd551f/genitmed00060-0021-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c680/1194271/4654a3201e86/genitmed00060-0022-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c680/1194271/756fe33fd708/genitmed00060-0022-b.jpg

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引用本文的文献

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Sex Transm Infect. 2005 Oct;81(5):415-8. doi: 10.1136/sti.2004.014407.
2
Anal human papillomavirus and anal cancer.肛门人乳头瘤病毒与肛门癌。
J Clin Pathol. 1997 Aug;50(8):625-34. doi: 10.1136/jcp.50.8.625.
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A comparison between cytology and histology to detect anal intraepithelial neoplasia.细胞学与组织学在检测肛管上皮内瘤变方面的比较。

本文引用的文献

1
Electron microscope observations on the human wart.人类疣的电子显微镜观察
Dermatologica. 1960 Oct;121:193-203. doi: 10.1159/000255270.
2
Anal smear test to diagnose occult anorectal infection with human papillomavirus in men.男性隐匿性肛门直肠人乳头瘤病毒感染的肛门涂片检测诊断
Br J Vener Dis. 1984 Jun;60(3):205. doi: 10.1136/sti.60.3.205.
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Intraepithelial carcinoma of the anus in homosexual men.
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Genitourin Med. 1994 Feb;70(1):22-5. doi: 10.1136/sti.70.1.22.
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Factors associated with clinical and sub-clinical anal human papillomavirus infection in homosexual men.男同性恋者临床及亚临床肛门人乳头瘤病毒感染的相关因素
Genitourin Med. 1991 Apr;67(2):92-8. doi: 10.1136/sti.67.2.92.
5
Anal intercourse: a risk factor for anal papillomavirus infection in women?肛交：女性肛门乳头瘤病毒感染的一个风险因素？
Genitourin Med. 1991 Dec;67(6):464-8. doi: 10.1136/sti.67.6.464.
6
Anal human papillomavirus infection: a comparative study of cytology, colposcopy and DNA hybridisation as methods of detection.肛管人乳头瘤病毒感染：作为检测方法的细胞学、阴道镜检查及DNA杂交的比较研究
Genitourin Med. 1991 Feb;67(1):21-5. doi: 10.1136/sti.67.1.21.
4
Human papillomavirus infection of the lower female genital tract: association with multicentric neoplasia.女性下生殖道人乳头瘤病毒感染：与多中心肿瘤形成的关联。
Int J Gynecol Pathol. 1983;2(3):264-74. doi: 10.1097/00004347-198303000-00004.
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Abnormalities of the uterine cervix in women with vulval warts. A preliminary communication.患有外阴湿疣的女性子宫颈异常。初步报告。
Br J Vener Dis. 1983 Apr;59(2):120-3. doi: 10.1136/sti.59.2.120.
6
Detection of human papillomavirus DNA in anogenital neoplasias.肛门生殖器肿瘤中人乳头瘤病毒DNA的检测
Nature. 1982 Dec 23;300(5894):771-3. doi: 10.1038/300771a0.
7
Noncondylomatous cervical wart virus infection.非尖锐湿疣性宫颈疣病毒感染
Obstet Gynecol. 1980 Apr;55(4):476-83.
8
Anorectal squamous carcinoma in two homosexual men.
Lancet. 1982 Aug 14;2(8294):391. doi: 10.1016/s0140-6736(82)90586-4.
9
Anal warts and anal coitus.肛门疣与肛交。
Br J Vener Dis. 1971 Oct;47(5):373-6. doi: 10.1136/sti.47.5.373.
10
Malignant transformation of condyloma acuminatum. A light microscopic and ultrastructural study.尖锐湿疣的恶性转化。光镜和超微结构研究。
Am J Clin Pathol. 1974 May;61(5):702-10. doi: 10.1093/ajcp/61.5.702.