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本文引用的文献

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Association of dietary nitrate with atherosclerotic vascular disease mortality: a prospective cohort study of older adult women.膳食硝酸盐与动脉粥样硬化性血管疾病死亡率的关联:一项针对老年女性的前瞻性队列研究。
Am J Clin Nutr. 2017 Jul;106(1):207-216. doi: 10.3945/ajcn.116.146761. Epub 2017 May 31.
2
Effects of a Hot-Water Extract of Allium hookeri Roots on Bone Formation in Human Osteoblast-Like MG-63 Cells In Vitro and in Rats In Vivo.胡葱根热水提取物对人成骨样MG-63细胞体外及大鼠体内骨形成的影响
Planta Med. 2016 Nov;82(16):1410-1415. doi: 10.1055/s-0042-108733. Epub 2016 Jun 9.
3
Fruit and Vegetable Intake and Hip Fracture Incidence in Older Men and Women: The CHANCES Project.老年男性和女性的水果和蔬菜摄入量与髋部骨折发生率:CHANCES项目
J Bone Miner Res. 2016 Sep;31(9):1743-52. doi: 10.1002/jbmr.2850. Epub 2016 Jun 8.
4
Increased intake of vegetables, but not fruits, may be associated with reduced risk of hip fracture: A meta-analysis.增加蔬菜摄入量而非水果摄入量可能与降低髋部骨折风险相关:一项荟萃分析。
Sci Rep. 2016 Jan 25;6:19783. doi: 10.1038/srep19783.
5
Apple intake is inversely associated with all-cause and disease-specific mortality in elderly women.老年女性摄入苹果与全因死亡率及特定疾病死亡率呈负相关。
Br J Nutr. 2016 Mar 14;115(5):860-7. doi: 10.1017/S0007114515005231. Epub 2016 Jan 20.
6
Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate.天然存在的异硫氰酸盐——萝卜硫素通过表观遗传调控对骨稳态进行合成代谢和抗吸收调节
J Biol Chem. 2016 Mar 25;291(13):6754-71. doi: 10.1074/jbc.M115.678235. Epub 2016 Jan 12.
7
Fruit and vegetable intake and risk of hip fracture: a cohort study of Swedish men and women.水果和蔬菜摄入量与髋部骨折风险:一项对瑞典男女的队列研究。
J Bone Miner Res. 2015 Jun;30(6):976-84. doi: 10.1002/jbmr.2384.
8
Sodium hydrosulfide inhibits the differentiation of osteoclast progenitor cells via NRF2-dependent mechanism.氢硫化钠通过NRF2依赖性机制抑制破骨细胞祖细胞的分化。
Pharmacol Res. 2014 Sep;87:99-112. doi: 10.1016/j.phrs.2014.06.014. Epub 2014 Jul 3.
9
Adherence to a vegetable-fruit-soy dietary pattern or the Alternative Healthy Eating Index is associated with lower hip fracture risk among Singapore Chinese.坚持蔬菜-水果-大豆饮食模式或替代健康饮食指数与新加坡华人髋部骨折风险降低相关。
J Nutr. 2014 Apr;144(4):511-8. doi: 10.3945/jn.113.187955. Epub 2014 Feb 26.
10
Development of the Melbourne FFQ: a food frequency questionnaire for use in an Australian prospective study involving an ethnically diverse cohort.墨尔本食物频率问卷的开发:一种用于澳大利亚一项涉及不同种族队列的前瞻性研究的食物频率问卷。
Asia Pac J Clin Nutr. 1994 Mar;3(1):19-31.

蔬菜和水果摄入量与骨折相关住院情况:一项针对老年女性的前瞻性研究

Vegetable and Fruit Intake and Fracture-Related Hospitalisations: A Prospective Study of Older Women.

作者信息

Blekkenhorst Lauren C, Hodgson Jonathan M, Lewis Joshua R, Devine Amanda, Woodman Richard J, Lim Wai H, Wong Germaine, Zhu Kun, Bondonno Catherine P, Ward Natalie C, Prince Richard L

机构信息

School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia, Perth, WA 6000, Australia.

School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia.

出版信息

Nutrients. 2017 May 18;9(5):511. doi: 10.3390/nu9050511.

DOI:10.3390/nu9050511
PMID:28524097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5452241/
Abstract

The importance of vegetable and fruit intakes for the prevention of fracture in older women is not well understood. Few studies have explored vegetable and fruit intakes separately, or the associations of specific types of vegetables and fruits with fracture hospitalisations. The objective of this study was to examine the associations of vegetable and fruit intakes, separately, and specific types of vegetables and fruits with fracture-related hospitalisations in a prospective cohort of women aged ≥70 years. Vegetable and fruit intakes were assessed at baseline (1998) in 1468 women using a food frequency questionnaire. The incidence of fracture-related hospitalisations over 14.5 years of follow-up was determined using the Hospital Morbidity Data Collection, linked via the Western Australian Data Linkage System. Fractures were identified in 415 (28.3%) women, of which 158 (10.8%) were hip fractures. Higher intakes of vegetables, but not fruits, were associated with lower fracture incidence. In multivariable-adjusted models for vegetable types, cruciferous and allium vegetables were inversely associated with all fractures, with a hazard ratio (HR) (95% confidence interval) of 0.72 (0.54, 0.95) and 0.66 (0.49, 0.88), respectively, for the highest vs. lowest quartiles. Increasing vegetable intake, with an emphasis on cruciferous and allium vegetables, may prevent fractures in older postmenopausal women.

摘要

蔬菜和水果摄入量对老年女性预防骨折的重要性尚未得到充分理解。很少有研究分别探讨蔬菜和水果的摄入量,或者特定种类的蔬菜和水果与骨折住院之间的关联。本研究的目的是在一个年龄≥70岁的女性前瞻性队列中,分别研究蔬菜和水果摄入量以及特定种类的蔬菜和水果与骨折相关住院之间的关联。使用食物频率问卷在基线时(1998年)对1468名女性的蔬菜和水果摄入量进行了评估。通过西澳大利亚数据链接系统,利用医院发病率数据收集确定了14.5年随访期间骨折相关住院的发生率。在415名(28.3%)女性中发现了骨折,其中158名(10.8%)为髋部骨折。蔬菜摄入量较高,但水果摄入量并非如此,与较低的骨折发生率相关。在针对蔬菜类型的多变量调整模型中,十字花科蔬菜和葱属蔬菜与所有骨折均呈负相关,最高四分位数与最低四分位数相比,风险比(HR)(95%置信区间)分别为0.72(0.54,0.95)和0.66(0.49,0.88)。增加蔬菜摄入量,尤其是十字花科蔬菜和葱属蔬菜,可能预防老年绝经后女性骨折。