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蔬菜和水果摄入量与骨折相关住院情况:一项针对老年女性的前瞻性研究

Vegetable and Fruit Intake and Fracture-Related Hospitalisations: A Prospective Study of Older Women.

作者信息

Blekkenhorst Lauren C, Hodgson Jonathan M, Lewis Joshua R, Devine Amanda, Woodman Richard J, Lim Wai H, Wong Germaine, Zhu Kun, Bondonno Catherine P, Ward Natalie C, Prince Richard L

机构信息

School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia, Perth, WA 6000, Australia.

School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia.

出版信息

Nutrients. 2017 May 18;9(5):511. doi: 10.3390/nu9050511.

Abstract

The importance of vegetable and fruit intakes for the prevention of fracture in older women is not well understood. Few studies have explored vegetable and fruit intakes separately, or the associations of specific types of vegetables and fruits with fracture hospitalisations. The objective of this study was to examine the associations of vegetable and fruit intakes, separately, and specific types of vegetables and fruits with fracture-related hospitalisations in a prospective cohort of women aged ≥70 years. Vegetable and fruit intakes were assessed at baseline (1998) in 1468 women using a food frequency questionnaire. The incidence of fracture-related hospitalisations over 14.5 years of follow-up was determined using the Hospital Morbidity Data Collection, linked via the Western Australian Data Linkage System. Fractures were identified in 415 (28.3%) women, of which 158 (10.8%) were hip fractures. Higher intakes of vegetables, but not fruits, were associated with lower fracture incidence. In multivariable-adjusted models for vegetable types, cruciferous and allium vegetables were inversely associated with all fractures, with a hazard ratio (HR) (95% confidence interval) of 0.72 (0.54, 0.95) and 0.66 (0.49, 0.88), respectively, for the highest vs. lowest quartiles. Increasing vegetable intake, with an emphasis on cruciferous and allium vegetables, may prevent fractures in older postmenopausal women.

摘要

蔬菜和水果摄入量对老年女性预防骨折的重要性尚未得到充分理解。很少有研究分别探讨蔬菜和水果的摄入量,或者特定种类的蔬菜和水果与骨折住院之间的关联。本研究的目的是在一个年龄≥70岁的女性前瞻性队列中,分别研究蔬菜和水果摄入量以及特定种类的蔬菜和水果与骨折相关住院之间的关联。使用食物频率问卷在基线时(1998年)对1468名女性的蔬菜和水果摄入量进行了评估。通过西澳大利亚数据链接系统,利用医院发病率数据收集确定了14.5年随访期间骨折相关住院的发生率。在415名(28.3%)女性中发现了骨折,其中158名(10.8%)为髋部骨折。蔬菜摄入量较高,但水果摄入量并非如此,与较低的骨折发生率相关。在针对蔬菜类型的多变量调整模型中,十字花科蔬菜和葱属蔬菜与所有骨折均呈负相关,最高四分位数与最低四分位数相比,风险比(HR)(95%置信区间)分别为0.72(0.54,0.95)和0.66(0.49,0.88)。增加蔬菜摄入量,尤其是十字花科蔬菜和葱属蔬菜,可能预防老年绝经后女性骨折。

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