Chen Mian, Cai Feiyan, Wang Chen, Wang Zhiyong, Meng Long, Li Fei, Zhang Pengfei, Liu Xin, Zheng Hairong
Paul C. Lauterbur Research Center for Biomedical Imaging Institute of Biomedical and Health Engineering Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China.
Adv Sci (Weinh). 2017 Feb 14;4(5):1600447. doi: 10.1002/advs.201600447. eCollection 2017 May.
Use of acoustic trapping for the manipulation of objects is invaluable to many applications from cellular subdivision to biological assays. Despite remarkable progress in a wide size range, the precise acoustic manipulation of 0D nanoparticles where all the structural dimensions are much smaller than the acoustic wavelength is still present challenges. This study reports on the observation of metal nanoparticles with different nanostructures for acoustic manipulation. Results for the first time exhibit that the hollow nanostructures play more important factor than size in the nanoscale acoustic manipulation. The acoustic levitation and swarm aggregations of the metal nanoparticles can be easily realized at low energy and clinically acceptable acoustic frequency by hollowing their nanostructures. In addition, the behaviors of swarm aggregations can be flexibly regulated by the applied voltage and frequency. This study anticipates that the strategy based on the unique properties of the metal hollow nanostructures and the manipulation method will be highly desirable for many applications.
声学捕获技术在从细胞细分到生物检测等众多应用中对物体的操控具有不可估量的价值。尽管在很宽的尺寸范围内已取得显著进展,但对于所有结构维度都远小于声波波长的零维纳米颗粒的精确声学操控仍存在挑战。本研究报告了对用于声学操控的具有不同纳米结构的金属纳米颗粒的观察结果。结果首次表明,在纳米级声学操控中,中空纳米结构比尺寸起着更重要的作用。通过使金属纳米颗粒的纳米结构中空,可在低能量和临床可接受的声频下轻松实现其声悬浮和群聚。此外,群聚行为可通过施加的电压和频率灵活调节。本研究预期,基于金属中空纳米结构独特性质的策略和操控方法将在许多应用中非常受欢迎。
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