Takahashi Toru, Okiura Aya, Kohno Masahiro
Toyo Institute of Food Technology, 23-2, 4-chome, Minami-Hanayashiki, Kawanishi, Hyogo, 666-0026, Japan.
Department of Bioengineering, Tokyo Institute of Technology, 4259-B1, Nagatsuta-cho, Midori-ku, Yokohama, 226-8502, Japan.
J Nat Med. 2017 Oct;71(4):770-775. doi: 10.1007/s11418-017-1093-6. Epub 2017 Jun 6.
The leaves of fig (Ficus carica L.) have been used for traditional and Chinese medicine. We determined the composition of phenylpropanoids (polyphenols and furanocoumarins) as a functional agent in the leaves of 37 cultivars of fig. The most abundant polyphenol was caffeoylmalic acid (12.0-26.6 mg/g dry weight), followed by rutin (4.7-14.6 mg/g dry weight) and isoschaftoside (2.5-6.4 mg/g dry weight). Psoralen (3.8-23.0 mg/g dry weight) was dominant in the furanocoumarins. In molar amounts, psoralic acid glucoside (PAG), a precursor of psoralen, was equivalent to psoralen. Furanocoumarins and PAG were not detected in the leaves of only one cultivar, Grise de Tarascon. Fig leaves are potentially an excellent source of polyphenols such as caffeoylmalic acid and rutin. From the result of cluster analysis, some cultivars that contained large amount of polyphenols, and a small amount (e.g., Grise de Saint Jean) or no (Grise de Tarascon) furanocoumarins, were found. These cultivars are considered suitable for functional foods or medicinal products.
无花果(Ficus carica L.)叶已被用于传统医学和中药。我们测定了37个无花果品种叶片中作为功能成分的苯丙烷类化合物(多酚和呋喃香豆素)的组成。含量最丰富的多酚是咖啡酰苹果酸(12.0 - 26.6毫克/克干重),其次是芦丁(4.7 - 14.6毫克/克干重)和异荭草苷(2.5 - 6.4毫克/克干重)。补骨脂素(3.8 - 23.0毫克/克干重)在呋喃香豆素中占主导地位。在摩尔量上,补骨脂素的前体补骨脂酸葡萄糖苷(PAG)与补骨脂素相当。仅在一个品种“Grise de Tarascon”的叶片中未检测到呋喃香豆素和PAG。无花果叶可能是咖啡酰苹果酸和芦丁等多酚的优质来源。从聚类分析结果来看,发现了一些含有大量多酚、少量(如“Grise de Saint Jean”)或不含(“Grise de Tarascon”)呋喃香豆素的品种。这些品种被认为适合用于功能性食品或药品。