Dimakopoulou Konstantina, Koutentakis Konstantinos, Papageorgiou Ifigeneia, Kasdagli Maria-Iosifina, Haralabidis Alexandros S, Sourtzi Panayota, Samoli Evangelia, Houthuijs Danny, Swart Wim, Hansell Anna L, Katsouyanni Klea
Department of Hygiene, Epidemiology and Medical Statistics, National and Kapodistrian University of Athens, Medical School, Athens, Greece / *joint second authors.
Section of Public Health, Department of Nursing, National and Kapodistrian University of Athens, Athens, Greece.
Occup Environ Med. 2017 Nov;74(11):830-837. doi: 10.1136/oemed-2016-104180. Epub 2017 Jun 13.
We followed up, in 2013, the subjects who lived near the Athens International Airport and had participated in the cross-sectional multicountry HYENA study in 2004-2006.
To evaluate the association of exposure to aircraft and road traffic noise with the incidence of hypertension and other cardiovascular outcomes.
From the 780 individuals who participated in the cross-sectional study, 537 were still living in the same area and 420 accepted to participate in the follow-up. Aircraft and road traffic noise exposure was based on the estimations conducted in 2004-2006, linking geocoded residential addresses of the participants to noise levels. We applied multiple logistic regression and Cox proportional hazards models, adjusting for potential confounders.
The incidence of hypertension was significantly associated with higher aircraft noise exposure during the night. Specifically, the OR for hypertension per 10 dB increase in Lnight aircraft noise exposure was 2.63 (95% CI 1.21 to 5.71). Doctor-diagnosed cardiac arrhythmia was significantly associated with Lnight aircraft noise exposure, when prevalent and incident cases were considered with an OR of 2.09 (95% CI 1.07 to 4.08). Stroke risk was also increased with increasing noise exposure but the association was not significant. Twenty-four-hour road traffic noise associations with the outcomes considered were weaker and less consistent.
In conclusion, our cohort study suggests that long-term exposure to aircraft noise, particularly during the night, is associated with incident hypertension and possibly, also, cardiovascular effects.
2013年，我们对居住在雅典国际机场附近且在2004年至2006年参与了多国横断面HYENA研究的受试者进行了随访。
评估暴露于飞机和道路交通噪声与高血压及其他心血管疾病发病之间的关联。
在参与横断面研究的780名个体中，537人仍居住在同一地区，420人同意参与随访。飞机和道路交通噪声暴露基于2004年至2006年进行的估算，将参与者的地理编码居住地址与噪声水平相关联。我们应用了多元逻辑回归和Cox比例风险模型，并对潜在混杂因素进行了调整。
高血压发病率与夜间较高的飞机噪声暴露显著相关。具体而言，夜间飞机噪声暴露每增加10分贝，高血压的比值比为2.63（95%置信区间为1.21至5.71）。当考虑现患和新发病例时，医生诊断的心律失常与夜间飞机噪声暴露显著相关，比值比为2.09（95%置信区间为1.07至4.08）。中风风险也随着噪声暴露的增加而增加，但这种关联不显著。24小时道路交通噪声与所考虑结果之间的关联较弱且不太一致。
总之，我们的队列研究表明，长期暴露于飞机噪声，尤其是在夜间，与高血压发病以及可能的心血管影响有关。
