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本文引用的文献

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The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2017/2018.《2017/2018年欧盟关于人畜共患病菌及人类、动物和食物中指示菌的抗菌药物耐药性总结报告》
EFSA J. 2020 Mar 3;18(3):e06007. doi: 10.2903/j.efsa.2020.6007. eCollection 2020 Mar.
2
The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2015.2015年欧盟关于人畜共患病及指示菌在人类、动物和食物中抗菌药物耐药性的总结报告。
EFSA J. 2017 Feb 23;15(2):e04694. doi: 10.2903/j.efsa.2017.4694. eCollection 2017 Feb.
3
The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2016.欧盟2016年人畜共患病、人畜共患病原体及食源性疾病暴发的趋势与来源总结报告
EFSA J. 2017 Dec 12;15(12):e05077. doi: 10.2903/j.efsa.2017.5077. eCollection 2017 Dec.
4
Antimicrobial-Resistant Campylobacter in Organically and Conventionally Raised Layer Chickens.有机饲养和传统饲养蛋鸡中的耐抗菌药弯曲杆菌
Foodborne Pathog Dis. 2017 Jan;14(1):29-34. doi: 10.1089/fpd.2016.2161. Epub 2016 Sep 22.
5
Antibiotic Resistance in Escherichia coli from Pigs in Organic and Conventional Farming in Four European Countries.来自四个欧洲国家有机和传统养殖猪的大肠杆菌中的抗生素耐药性
PLoS One. 2016 Jun 30;11(6):e0157049. doi: 10.1371/journal.pone.0157049. eCollection 2016.
6
Monitoring Antimicrobial Resistance in the Food Supply Chain and Its Implications for FDA Policy Initiatives.监测食品供应链中的抗菌药物耐药性及其对美国食品药品监督管理局政策举措的影响。
Antimicrob Agents Chemother. 2016 Aug 22;60(9):5302-11. doi: 10.1128/AAC.00688-16. Print 2016 Sep.
7
Molecular subtyping and erythromycin resistance of Campylobacter in China.中国弯曲杆菌的分子分型及红霉素耐药性
J Appl Microbiol. 2016 Jul;121(1):287-93. doi: 10.1111/jam.13135. Epub 2016 May 9.
8
Impact of colistin sulfate treatment of broilers on the presence of resistant bacteria and resistance genes in stored or composted manure.硫酸黏菌素治疗肉鸡对储存或堆肥粪便中耐药菌及耐药基因存在情况的影响
Vet Microbiol. 2016 Oct 15;194:98-106. doi: 10.1016/j.vetmic.2015.11.012. Epub 2015 Nov 17.
9
Description of an erm(B)-carrying Campylobacter coli isolate in Europe.欧洲一株携带erm(B)的空肠弯曲菌分离株的描述。
J Antimicrob Chemother. 2016 Mar;71(3):841-3. doi: 10.1093/jac/dkv383. Epub 2015 Nov 24.
10
EUCAST recommendations for antimicrobial susceptibility testing applied to the three main Campylobacter species isolated in humans.欧洲抗菌药物敏感性试验委员会(EUCAST)针对人类分离出的三种主要弯曲杆菌属细菌的抗菌药物敏感性试验建议。
J Microbiol Methods. 2015 Dec;119:206-13. doi: 10.1016/j.mimet.2015.10.018. Epub 2015 Nov 11.

法国和瑞典有机与传统养猪生产中的:患病率与抗菌药物耐药性

in Organic and Conventional Pig Production in France and Sweden: Prevalence and Antimicrobial Resistance.

作者信息

Kempf Isabelle, Kerouanton Annaelle, Bougeard Stéphanie, Nagard Bérengère, Rose Valérie, Mourand Gwénaëlle, Osterberg Julia, Denis Martine, Bengtsson Björn O

机构信息

French Agency for Food, Environmental and Occupational Health and Safety (Anses), Mycoplasmology - Bacteriology Unit, Bretagne Loire UniversityPloufragan, France.

French Agency for Food, Environmental and Occupational Health and Safety (Anses), Hygiene and Quality of Poultry and Pig Products Unit, Bretagne Loire UniversityPloufragan, France.

出版信息

Front Microbiol. 2017 May 29;8:955. doi: 10.3389/fmicb.2017.00955. eCollection 2017.

DOI:10.3389/fmicb.2017.00955
PMID:28611754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5447011/
Abstract

The purpose of the study was to evaluate and compare the prevalence and antimicrobial resistance of in conventional and organic pigs from France and Sweden. Fecal or colon samples were collected at farms or at slaughterhouses and cultured for . The minimum inhibitory concentrations of ciprofloxacin, nalidixic acid, streptomycin, tetracycline, erythromycin, and gentamicin were determined by microdilution for a total of 263 French strains from 114 pigs from 50 different farms and 82 Swedish strains from 144 pigs from 54 different farms. Erythromycin resistant isolates were examined for presence of the emerging rRNA methylase (B) gene. The study showed that within the colon samples obtained in each country there was no significant difference in prevalence of between pigs in organic and conventional productions [France: conventional: 43/58 (74%); organic: 43/56 (77%) and Sweden: conventional: 24/36 (67%); organic: 20/36 (56%)]. In France, but not in Sweden, significant differences of percentages of resistant isolates were associated with production type (tetracycline, erythromycin) and the number of resistances was significantly higher for isolates from conventional pigs. In Sweden, the number of resistances of fecal isolates was significantly higher compared to colon isolates. The (B) gene was not detected in the 87 erythromycin resistant strains tested.

摘要

本研究的目的是评估和比较法国和瑞典传统养殖与有机养殖猪的[某种细菌]流行率及抗菌药物耐药性。在养殖场或屠宰场采集粪便或结肠样本,并对[某种细菌]进行培养。采用微量稀释法测定了来自法国50个不同养殖场114头猪的263株菌株以及来自瑞典54个不同养殖场144头猪的82株菌株对环丙沙星、萘啶酸、链霉素、四环素、红霉素和庆大霉素的最低抑菌浓度。对红霉素耐药菌株检测新兴的rRNA甲基化酶(B)基因的存在情况。研究表明,在每个国家采集的结肠样本中,有机养殖和传统养殖猪的[某种细菌]流行率无显著差异[法国:传统养殖:43/58(74%);有机养殖:43/56(77%);瑞典:传统养殖:24/36(67%);有机养殖:20/36(56%)]。在法国,而非瑞典,耐药菌株百分比的显著差异与养殖类型有关(四环素、红霉素),且传统养殖猪分离株的耐药数量显著更高。在瑞典,粪便分离株的耐药数量相比结肠分离株显著更高。在所检测的87株红霉素耐药菌株中未检测到(B)基因。