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J Clin Med Res. 2017 Jul;9(7):547-554. doi: 10.14740/jocmr3032w. Epub 2017 May 22.
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Childhood hospitalisation with infection and cardiovascular disease in early-mid adulthood: a longitudinal population-based study.儿童期因感染住院与成年早期至中期的心血管疾病：一项基于人群的纵向研究。
PLoS One. 2015 May 4;10(5):e0125342. doi: 10.1371/journal.pone.0125342. eCollection 2015.
2
Infectious burden and atherosclerosis: A clinical issue.感染负担与动脉粥样硬化：一个临床问题。
World J Clin Cases. 2014 Jul 16;2(7):240-9. doi: 10.12998/wjcc.v2.i7.240.
3
Persistent C. pneumoniae infection in atherosclerotic lesions: rethinking the clinical trials.动脉粥样硬化病变中肺炎衣原体的持续感染：对临床试验的重新思考
Front Cell Infect Microbiol. 2014 Mar 21;4:34. doi: 10.3389/fcimb.2014.00034. eCollection 2014.
4
Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection.早期细胞因子血症与干扰素诱导跨膜蛋白 3 功能障碍有关，并可预测 H7N9 感染的致命性。
Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):769-74. doi: 10.1073/pnas.1321748111. Epub 2013 Dec 23.
5
Supra-additive expression of interleukin-6, interleukin-8 and basic fibroblast growth factor in vascular smooth muscle cells following coinfection with Chlamydia pneumoniae and cytomegalovirus as a novel link between infection and atherosclerosis.肺炎衣原体和巨细胞病毒共同感染后血管平滑肌细胞中白细胞介素-6、白细胞介素-8 和碱性成纤维细胞生长因子的过表达作为感染与动脉粥样硬化之间的新联系。
Can J Infect Dis Med Microbiol. 2012 Summer;23(2):e26-30. doi: 10.1155/2012/987476.
6
Cytomegalovirus exposure and cardiovascular disease in kidney transplant recipients.巨细胞病毒感染与肾移植受者的心血管疾病
J Infect Dis. 2013 May 15;207(10):1569-75. doi: 10.1093/infdis/jit064. Epub 2013 Feb 15.
7
Atherosclerosis and infection: is the jury still not in?动脉粥样硬化与感染：陪审团仍未做出裁决？
Future Microbiol. 2012 Oct;7(10):1217-30. doi: 10.2217/fmb.12.87.
8
Cytomegalovirus localization in atherosclerotic plaques is associated with acute coronary syndromes: report of 105 patients.巨细胞病毒在动脉粥样硬化斑块中的定位与急性冠状动脉综合征相关：105例患者的报告
Methodist Debakey Cardiovasc J. 2012 Apr-Jun;8(2):42-6. doi: 10.14797/mdcj-8-2-42.
9
Lifetime risks of cardiovascular disease.心血管疾病的终身风险。
N Engl J Med. 2012 Jan 26;366(4):321-9. doi: 10.1056/NEJMoa1012848.
10
Pathogens and atherosclerosis: update on the potential contribution of multiple infectious organisms to the pathogenesis of atherosclerosis.病原体与动脉粥样硬化：多种感染病原体在动脉粥样硬化发病机制中的潜在作用的最新研究进展。
Thromb Haemost. 2011 Nov;106(5):858-67. doi: 10.1160/TH11-06-0392. Epub 2011 Oct 20.

关于感染在动脉粥样硬化发病机制中的潜在作用的一场未解决的争论。

An Unsettled Debate About the Potential Role of Infection in Pathogenesis of Atherosclerosis.

作者信息

Dahal Udip, Sharma Dikshya, Dahal Kumud

机构信息

Department of Medicine, University of Utah, 50 N Medical Drive, Salt Lake City, UT, USA.

Department of Internal Medicine, Staten Island University Hospital, 475 Seaview Avenue, Staten Island, NY, USA.

出版信息

J Clin Med Res. 2017 Jul;9(7):547-554. doi: 10.14740/jocmr3032w. Epub 2017 May 22.

DOI:10.14740/jocmr3032w
PMID:28611853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5458650/
Abstract

Association of infection with atherosclerosis is by no means new. Several sero-epidemiological and pathologic studies as well as animal models have shown a link between infection and atherosclerosis. Exciting discoveries in recent times related to role of inter-individual genetic variation in modulating inflammatory response to infection have reignited the enthusiasm in proving a causal link between infection and atherosclerosis. The purpose of this article was to review and analyze the available evidence linking infection with atherosclerosis.

摘要

感染与动脉粥样硬化之间的关联绝非新鲜事。多项血清流行病学和病理学研究以及动物模型均已表明感染与动脉粥样硬化之间存在联系。近期有关个体间基因变异在调节对感染的炎症反应中所起作用的激动人心的发现，再度燃起了人们证明感染与动脉粥样硬化之间存在因果关系的热情。本文旨在综述和分析将感染与动脉粥样硬化联系起来的现有证据。