Department of Prosthodontics, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Clin Implant Dent Relat Res. 2017 Oct;19(5):770-775. doi: 10.1111/cid.12510. Epub 2017 Jun 20.
Chemical modifications of the dental implant surface that improve the wettability result in a faster and better osseointegration.
The aim of this randomized clinical trial was to evaluate the implant stability quotient (ISQ) of implants with similar designs, treated with 2 surfaces, sandblasted acid-etched (SAE) and hydrophilic SAE, within the initial 16 weeks of healing.
A total of 64 implants (32 SAE-control group and 32 modified SAE-test group) with the same design, length, and diameter (conical and compressive, 4.3 × 10 mm) were inserted into the posterior maxillae of 21 patients partially edentulous. The ISQ values were collected at post-surgery (T0), 1 week (T1), 2 weeks (T2), 3 weeks (T3), 5 weeks (T4), 8 weeks (T5), 12 weeks (T6), and 16 weeks (T7).
None of the implants failed. Test group presented ISQ values higher than the control group (ANOVA-P < .01) from T5 to T7. When comparing groups regarding the amount of time required to achieve ISQ ≥ 70 as a reference, there was a statistically significant difference (cox regression-P < .01), and a hazard ratio of 2.24 (CI 1.62-3.11). At the 1-year follow-up, there was a drop out of 1 patient, and 2 implants were no longer evaluated. Survival rate for both groups was 100% at the 1-year follow-up.
The current study suggests that implants with hydrophilic surface (modified SAE) integrate faster than implants with SAE surface. The stability gain of the test group was 2.24 times faster than the control group after 5 weeks of evaluation at the posterior region of the edentulous maxillae.
改善种植牙表面润湿性的化学修饰可加速并改善骨整合。
本随机临床试验的目的是评估在愈合的最初 16 周内,具有相似设计的种植体的种植体稳定性指数(ISQ),这些种植体采用喷砂酸蚀(SAE)和亲水 SAE 两种表面处理。
共将 64 枚设计、长度和直径(锥形、压缩型,4.3×10mm)相同的种植体(32 枚 SAE-对照组和 32 枚改良 SAE-实验组)植入 21 名部分缺牙患者的上颌后牙区。在手术后(T0)、1 周(T1)、2 周(T2)、3 周(T3)、5 周(T4)、8 周(T5)、12 周(T6)和 16 周(T7)时收集 ISQ 值。
无一例种植体失败。实验组的 ISQ 值从 T5 到 T7 均高于对照组(ANOVA-P<.01)。比较两组达到 ISQ≥70 作为参考所需的时间量时,差异有统计学意义(cox 回归-P<.01),风险比为 2.24(CI 1.62-3.11)。在 1 年的随访中,有 1 名患者脱落,2 枚种植体不再进行评估。两组在 1 年随访时的存活率均为 100%。
本研究表明,亲水表面(改良 SAE)的种植体比 SAE 表面的种植体更快地整合。在对无牙上颌后牙区进行 5 周评估后,实验组的稳定性增益比对照组快 2.24 倍。