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国际病毒分类委员会病毒分类概况:多瘤病毒科

ICTV Virus Taxonomy Profile: Polyomaviridae.

作者信息

Moens Ugo, Calvignac-Spencer Sébastien, Lauber Chris, Ramqvist Torbjörn, Feltkamp Mariet C W, Daugherty Matthew D, Verschoor Ernst J, Ehlers Bernhard

机构信息

University of Tromsø, 9037 Tromsø, Norway.

Robert Koch Institute, 13353 Berlin, Germany.

出版信息

J Gen Virol. 2017 Jun;98(6):1159-1160. doi: 10.1099/jgv.0.000839. Epub 2017 Jun 22.

Abstract

The Polyomaviridae is a family of small, non-enveloped viruses with circular dsDNA genomes of approximately 5 kbp. The family includes four genera whose members have restricted host range, infecting mammals and birds. Polyomavirus genomes have also been detected recently in fish. Merkel cell polyomavirus and raccoon polyomavirus are associated with cancer in their host; other members are human and veterinary pathogens. Clinical manifestations are obvious in immunocompromised patients but not in healthy individuals. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the Polyomaviridae, which is available at www.ictv.global/report/polyomaviridae.

摘要

多瘤病毒科是一类小型无包膜病毒,其环状双链DNA基因组大小约为5千碱基对。该科包括四个属,其成员宿主范围有限,感染哺乳动物和鸟类。最近在鱼类中也检测到了多瘤病毒基因组。默克尔细胞多瘤病毒和浣熊多瘤病毒与宿主的癌症有关;其他成员是人类和兽医病原体。临床表现在免疫功能低下的患者中明显,但在健康个体中不明显。这是国际病毒分类委员会(ICTV)关于多瘤病毒科分类的报告摘要,该报告可在www.ictv.global/report/polyomaviridae上获取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6519/5656788/803e243ce671/jgv-98-1159-g001.jpg

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