Sakuraya Asuka, Watanabe Kazuhiro, Kawakami Norito, Imamura Kotaro, Ando Emiko, Asai Yumi, Eguchi Hisashi, Kobayashi Yuka, Nishida Norimitsu, Arima Hideaki, Shimazu Akihito, Tsutsumi Akizumi
Department of Mental Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
The Japan Society for the Promotion of Science, Tokyo, Japan.
BMJ Open. 2017 Jun 22;7(6):e016716. doi: 10.1136/bmjopen-2017-016716.
Metabolic syndrome is an important public health target because of its high prevalence worldwide. Work-related psychosocial factors have been identified as determinants of metabolic syndrome components. However, there have been no systematic reviews or meta-analyses conducted to evaluate the relationship between work-related psychosocial factors and metabolic syndrome as an aggregated cluster. The aim of this study is to examine this association from published prospective studies.
The systematic review and meta-analysis will be conducted using published studies that will be identified from electronic databases (ie, PubMed, EMBASE, PsycINFO, PsycARTICLES and Japan Medical Abstracts Society). Studies that (1) examined the association between work-related psychosocial factors and the onset of metabolic syndrome, (2) had a longitudinal or prospective cohort design, (3) were conducted among workers, (4) provided sufficient data for calculating ORs or relative risk with a 95% CI, (5) were published as original articles written in English or Japanese, and (6) having been published until the end of 2016 will be included. Study selection, data collection, quality assessment and statistical syntheses will be conducted based on discussions among investigators.
Ethics approval was not required for this study because it was based on published studies. The results and findings of this study will be submitted and published in a scientific peer-reviewed journal. The findings from this study could be useful for assessing metabolic syndrome risk factors in the workplace, and determining approaches for prevention of metabolic syndrome in the future.
PROSPERO CRD42016039096 (http://www.crd.york.ac.uk/PROSPERO_REBRANDING/display_record.asp?ID=CRD42016039096).
代谢综合征因其在全球的高患病率而成为重要的公共卫生目标。工作相关的社会心理因素已被确定为代谢综合征各组成部分的决定因素。然而,尚未进行系统评价或荟萃分析来评估工作相关的社会心理因素与作为一个综合集群的代谢综合征之间的关系。本研究的目的是从已发表的前瞻性研究中检验这种关联。
将使用从电子数据库(即PubMed、EMBASE、PsycINFO、PsycARTICLES和日本医学摘要协会)中识别出的已发表研究进行系统评价和荟萃分析。纳入的研究需满足以下条件:(1)研究工作相关的社会心理因素与代谢综合征发病之间的关联;(2)采用纵向或前瞻性队列设计;(3)在工人中进行;(4)提供足够数据以计算95%可信区间的比值比(OR)或相对风险;(5)以英文或日文发表的原创文章形式发表;(6)截至2016年底已发表。将根据研究人员之间的讨论进行研究选择、数据收集、质量评估和统计综合分析。
本研究无需伦理批准,因为它基于已发表的研究。本研究的结果和发现将提交并发表在科学同行评审期刊上。本研究的发现可能有助于评估工作场所代谢综合征的危险因素,并确定未来预防代谢综合征的方法。
PROSPERO CRD42016039096(http://www.crd.york.ac.uk/PROSPERO_REBRANDING/display_record.asp?ID=CRD42016039096)