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两例结肠镜检查时表现为淡黄色至白色病变的直肠黄色瘤病例。

Two Cases of Rectal Xanthoma Presenting as Yellowish to Whitish Lesions during Colonoscopy.

作者信息

Iwamuro Masaya, Tanaka Takehiro, Takei Daisuke, Sugihara Yuusaku, Harada Keita, Hiraoka Sakiko, Kawahara Yoshiro, Okada Hiroyuki

机构信息

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.

Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.

出版信息

Case Rep Gastrointest Med. 2017;2017:5975107. doi: 10.1155/2017/5975107. Epub 2017 Jun 1.

DOI:10.1155/2017/5975107
PMID:28656115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5471581/
Abstract

Two cases of rectal xanthomas are described. One case is that of a 56-year-old Japanese man in whom multiple yellowish spots measuring approximately 3 to 5 mm were observed in the rectum during colonoscopy. The other case is that of a 78-year-old Japanese man in whom colonoscopy showed a whitish plaque of 4 mm in diameter in the rectum. Biopsy examinations performed on both patients revealed the deposition of xanthoma cells within the rectal mucosa. Within the gastrointestinal tract, xanthomas most frequently arise in the stomach, whereas the colorectum is rarely affected. Despite this infrequency, the two cases indicate that xanthomas should be recalled when yellowish to whitish lesions are observed in the colorectum.

摘要

本文描述了两例直肠黄色瘤病例。一例是一名56岁的日本男性,在结肠镜检查时,其直肠内发现多个大小约为3至5毫米的淡黄色斑点。另一例是一名78岁的日本男性,结肠镜检查显示其直肠内有一个直径为4毫米的白色斑块。对两名患者进行的活检检查均显示直肠黏膜内有黄色瘤细胞沉积。在胃肠道中,黄色瘤最常发生于胃,而结直肠很少受累。尽管发生率较低,但这两例病例表明,当在结直肠中观察到淡黄色至白色病变时,应考虑黄色瘤的可能。

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本文引用的文献

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Xanthoma of the Duodenum.十二指肠黄瘤
Intern Med. 2016;55(19):2899-2900. doi: 10.2169/internalmedicine.55.6993. Epub 2016 Oct 1.
2
Colorectal Manifestation of Follicular Lymphoma.滤泡性淋巴瘤的结直肠表现
Intern Med. 2016;55(1):1-8. doi: 10.2169/internalmedicine.55.5393. Epub 2016 Jan 1.
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Caecum lipoma: a rare cause of lower gastrointestinal bleeding.盲肠脂肪瘤:下消化道出血的罕见病因。
BMJ Case Rep. 2014 Sep 23;2014:bcr2014206526. doi: 10.1136/bcr-2014-206526.
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Pseudomembranous Colitis: Not Always Caused by Clostridium difficile.伪膜性结肠炎:并非总是由艰难梭菌引起。
Case Rep Med. 2014;2014:812704. doi: 10.1155/2014/812704. Epub 2014 Aug 18.
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Xanthomatous hyperplastic polyps of the stomach: clinicopathologic study of 5 patients with polypoid gastric lesions showing combined features of gastric xanthelasma and hyperplastic polyp.胃黄色瘤样增生性息肉:5 例表现为胃黄色瘤和增生性息肉特征混合的息肉样胃病变患者的临床病理研究。
Ann Diagn Pathol. 2013 Feb;17(1):72-4. doi: 10.1016/j.anndiagpath.2012.08.001. Epub 2012 Sep 26.
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Xanthomas of the stomach: a report of two cases.胃黄色瘤:两例报告。
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Macrophage-related diseases of the gut: a pathologist's perspective.肠道相关巨噬细胞疾病:病理学家的视角。
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70-year-old female presenting with rectosigmoid (colonic) xanthoma and multiple benign polyps - case report.70岁女性,患有直肠乙状结肠(结肠)黄色瘤和多发性良性息肉——病例报告。
Pol J Pathol. 2010;61(1):42-5.
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Xanthoma disseminatum with large plaques confined to the back, pulmonary involvement and multiple intestinal xanthomas.
Dermatology. 2004;208(2):164-6. doi: 10.1159/000076494.
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Colorectal xanthomas with polypoid lesion: report of 25 cases.伴有息肉样病变的大肠黄色瘤:25例报告
APMIS. 2004 Jan;112(1):3-10. doi: 10.1111/j.1600-0463.2004.apm1120102.x.