Fang Lin, Wang Weiqi, Liu Yang, Xie Zhigang, Chen Li
Department of Chemistry, Northeast Normal University, 5268 Remin Street, Changchun 130024, P. R. China.
Dalton Trans. 2017 Jul 18;46(28):8933-8937. doi: 10.1039/c7dt00613f.
Metal-Organic Frameworks (MOFs) were exploited to coat Au nanorods (AuNRs) as a hyperthermia agent for enhanced plasmonic photothermal therapy. The utilization of a MOF shell reduces the cytotoxicity of AuNRs and enhances the photothermal transduction efficiency of AuNRs, resulting in the improved phototoxicity of MOF coated AuNRs compared with the unmodified AuNRs.
金属有机框架材料(MOFs)被用于包覆金纳米棒(AuNRs),作为一种用于增强等离子体光热疗法的热疗剂。MOF壳层的使用降低了AuNRs的细胞毒性,并提高了AuNRs的光热转换效率,与未修饰的AuNRs相比,MOF包覆的AuNRs的光毒性得到了改善。