Boosting endogenous production of vasoprotective hydrogen sulfide via supplementation with taurine and N-acetylcysteine: a novel way to promote cardiovascular health.
作者信息
DiNicolantonio James J, OKeefe James H, McCarty Mark F
机构信息
Saint Luke's Mid America Heart Institute, Kansas City, Missouri, USA.
Catalytic Longevity, Encinitas, California, USA.
出版信息
Open Heart. 2017 May 22;4(1):e000600. doi: 10.1136/openhrt-2017-000600. eCollection 2017.
Abstract
摘要
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Boosting endogenous production of vasoprotective hydrogen sulfide via supplementation with taurine and N-acetylcysteine: a novel way to promote cardiovascular health.通过补充牛磺酸和N-乙酰半胱氨酸来提高内源性血管保护硫化氢的产生：一种促进心血管健康的新方法。
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本文引用的文献
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The interaction of estrogen and CSE/HS pathway in the development of atherosclerosis.雌激素与CSE/HS途径在动脉粥样硬化发展中的相互作用。
Am J Physiol Heart Circ Physiol. 2017 Mar 1;312(3):H406-H414. doi: 10.1152/ajpheart.00245.2016. Epub 2016 Dec 16.
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The effects of hydrogen sulfide on platelet-leukocyte aggregation and microvascular thrombolysis.硫化氢对血小板-白细胞聚集及微血管溶栓的影响。
Platelets. 2017 Jul;28(5):509-517. doi: 10.1080/09537104.2016.1235693. Epub 2016 Nov 7.
3
Hydrogen sulfide, an enhancer of vascular nitric oxide signaling: mechanisms and implications.硫化氢，一种血管一氧化氮信号传导的增强剂：作用机制及意义
Am J Physiol Cell Physiol. 2017 Jan 1;312(1):C3-C15. doi: 10.1152/ajpcell.00282.2016. Epub 2016 Oct 26.
4
Hydrogen sulfide-induced vasodilation mediated by endothelial TRPV4 channels.内皮TRPV4通道介导的硫化氢诱导的血管舒张
Am J Physiol Heart Circ Physiol. 2016 Dec 1;311(6):H1437-H1444. doi: 10.1152/ajpheart.00465.2016. Epub 2016 Oct 7.
5
Hydrogen Sulfide Regulates Krüppel-Like Factor 5 Transcription Activity via Specificity Protein 1 S-Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy.硫化氢通过特异性蛋白 1 半胱氨酸 664 上的 S-巯基化调节 Krüppel 样因子 5 的转录活性，以防止心肌肥大。
J Am Heart Assoc. 2016 Sep 16;5(9):e004160. doi: 10.1161/JAHA.116.004160.
6
Regulation and role of endogenously produced hydrogen sulfide in angiogenesis.内源性硫化氢在血管生成中的调节作用
Pharmacol Res. 2016 Nov;113(Pt A):175-185. doi: 10.1016/j.phrs.2016.08.026. Epub 2016 Aug 26.
7
Asymmetric Dimethylarginine Is a Well Established Mediating Risk Factor for Cardiovascular Morbidity and Mortality-Should Patients with Elevated Levels Be Supplemented with Citrulline?不对称二甲基精氨酸是心血管疾病发病和死亡的既定中介危险因素——血液中该水平升高的患者是否应补充瓜氨酸？
Healthcare (Basel). 2016 Jul 8;4(3):40. doi: 10.3390/healthcare4030040.
8
Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide.硫化氢对可溶性鸟苷酸环化酶氧化还原状态的调节
Pharmacol Res. 2016 Sep;111:556-562. doi: 10.1016/j.phrs.2016.06.029. Epub 2016 Jul 1.
9
Hydrogen Sulfide Induces Keap1 S-sulfhydration and Suppresses Diabetes-Accelerated Atherosclerosis via Nrf2 Activation.硫化氢通过激活Nrf2诱导Keap1的S-巯基化并抑制糖尿病加速的动脉粥样硬化。
Diabetes. 2016 Oct;65(10):3171-84. doi: 10.2337/db16-0020. Epub 2016 Jun 22.
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Hydrogen sulfide exhibits cardioprotective effects by decreasing endoplasmic reticulum stress in a diabetic cardiomyopathy rat model.在糖尿病性心肌病大鼠模型中，硫化氢通过降低内质网应激发挥心脏保护作用。
Mol Med Rep. 2016 Jul;14(1):865-73. doi: 10.3892/mmr.2016.5289. Epub 2016 May 17.
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