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The New Macromolecular Femtosecond Crystallography (MFX) Instrument at LCLS.直线加速器相干光源处的新型大分子飞秒晶体学（MFX）仪器。
Synchrotron Radiat News. 2016;29(1):23-28. doi: 10.1080/08940886.2016.1124681. Epub 2016 Feb 1.
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The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source.直线加速器相干光源处的大分子飞秒晶体学仪器。
J Synchrotron Radiat. 2019 Mar 1;26(Pt 2):346-357. doi: 10.1107/S1600577519001577. Epub 2019 Feb 22.
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Se-SAD serial femtosecond crystallography datasets from selenobiotinyl-streptavidin.来自硒代生物素化链霉亲和素的 Se-SAD 序列飞秒晶体学数据集。
Sci Data. 2017 Apr 25;4:170055. doi: 10.1038/sdata.2017.55.
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Time-Resolved Macromolecular Crystallography at Pulsed X-ray Sources.脉冲 X 射线源的时间分辨大分子晶体学。
Int J Mol Sci. 2019 Mar 20;20(6):1401. doi: 10.3390/ijms20061401.
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Mix-and-Inject Serial Femtosecond Crystallography to Capture RNA Riboswitch Intermediates.混合注入式连续飞秒晶体学捕获 RNA 核糖开关中间态
Methods Mol Biol. 2023;2568:243-249. doi: 10.1007/978-1-0716-2687-0_16.
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Fixed target matrix for femtosecond time-resolved and in situ serial micro-crystallography.用于飞秒时间分辨和原位连续微晶体学的固定靶矩阵。
Struct Dyn. 2015 Aug 18;2(5):054302. doi: 10.1063/1.4928706. eCollection 2015 Sep.
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Neutron macromolecular crystallography at the European spallation source.中子大分子晶体学在欧洲散裂源上的应用。
Methods Enzymol. 2020;634:125-151. doi: 10.1016/bs.mie.2020.01.005. Epub 2020 Feb 7.
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Two mirror X-ray pulse split and delay instrument for femtosecond time resolved investigations at the LCLS free electron laser facility.用于LCLS自由电子激光装置飞秒时间分辨研究的双镜X射线脉冲分裂与延迟仪。
Opt Express. 2016 May 30;24(11):11768-81. doi: 10.1364/OE.24.011768.
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Economic evaluation of single-fraction versus multiple-fraction palliative radiotherapy for painful bone metastases in breast, lung and prostate cancer.乳腺癌、肺癌和前列腺癌疼痛性骨转移的单次分割与多次分割姑息性放疗的经济学评估。
J Med Imaging Radiat Oncol. 2016 Oct;60(5):650-660. doi: 10.1111/1754-9485.12467. Epub 2016 May 13.
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Fifteen years of the Protein Crystallography Station: the coming of age of macromolecular neutron crystallography.蛋白质晶体学站的十五年：大分子中子晶体学的成熟
IUCrJ. 2017 Jan 1;4(Pt 1):72-86. doi: 10.1107/S205225251601664X.
引用本文的文献
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Observation of early events in the photoactivation of Myxobacterial phytochrome using time-resolved serial femtosecond crystallography.利用时间分辨串联飞秒晶体学观察粘细菌光敏色素光激活的早期事件。
Commun Chem. 2025 Jun 12;8(1):183. doi: 10.1038/s42004-025-01578-z.
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Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.转录的结构基础：使用自由电子激光研究 RNA 聚合酶 II 底物结合和金属配位。
Proc Natl Acad Sci U S A. 2024 Sep 3;121(36):e2318527121. doi: 10.1073/pnas.2318527121. Epub 2024 Aug 27.
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Explainable machine learning for diffraction patterns.用于衍射图案的可解释机器学习。
J Appl Crystallogr. 2023 Sep 20;56(Pt 5):1494-1504. doi: 10.1107/S1600576723007446. eCollection 2023 Oct 1.
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Heterogeneity in M. tuberculosis β-lactamase inhibition by Sulbactam.利奈唑胺对结核分枝杆菌β-内酰胺酶的抑制作用存在异质性。
Nat Commun. 2023 Sep 7;14(1):5507. doi: 10.1038/s41467-023-41246-1.
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Data reduction for X-ray serial crystallography using machine learning.利用机器学习进行X射线串行晶体学的数据约简
J Appl Crystallogr. 2023 Feb 1;56(Pt 1):200-213. doi: 10.1107/S1600576722011748.
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Electrically stimulated droplet injector for reduced sample consumption in serial crystallography.用于串行晶体学中减少样品消耗的电刺激液滴注射器。
Biophys Rep (N Y). 2022 Sep 29;2(4):100081. doi: 10.1016/j.bpr.2022.100081. eCollection 2022 Dec 14.
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X-ray free-electron laser studies reveal correlated motion during isopenicillin synthase catalysis.X 射线自由电子激光研究揭示了异青霉素合成酶催化过程中的关联运动。
Sci Adv. 2021 Aug 20;7(34). doi: 10.1126/sciadv.abh0250. Print 2021 Aug.
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Towards the spatial resolution of metalloprotein charge states by detailed modeling of XFEL crystallographic diffraction.通过详细建模 XFEL 晶体学衍射，实现金属蛋白电荷态的空间分辨率。
Acta Crystallogr D Struct Biol. 2020 Feb 1;76(Pt 2):176-192. doi: 10.1107/S2059798320000418. Epub 2020 Feb 4.
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Ultracompact 3D microfluidics for time-resolved structural biology.用于时间分辨结构生物学的超紧凑 3D 微流控技术。
Nat Commun. 2020 Jan 31;11(1):657. doi: 10.1038/s41467-020-14434-6.
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3D printed droplet generation devices for serial femtosecond crystallography enabled by surface coating.通过表面涂层实现的用于串行飞秒晶体学的3D打印微滴生成装置
J Appl Crystallogr. 2019 Aug 29;52(Pt 5):997-1008. doi: 10.1107/S1600576719010343. eCollection 2019 Oct 1.
本文引用的文献
1
Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.通过多温度和X射线自由电子激光晶体学绘制动态酶的构象图谱。
Elife. 2015 Sep 30;4:e07574. doi: 10.7554/eLife.07574.
2
Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis.用于神经元胞吐作用的突触结合蛋白-SNARE机制的结构
Nature. 2015 Sep 3;525(7567):62-7. doi: 10.1038/nature14975. Epub 2015 Aug 17.
3
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.通过飞秒X射线激光获得的视紫红质与抑制蛋白结合的晶体结构。
Nature. 2015 Jul 30;523(7562):561-7. doi: 10.1038/nature14656. Epub 2015 Jul 22.
4
Demonstration of simultaneous experiments using thin crystal multiplexing at the Linac Coherent Light Source.直线加速器相干光源处使用薄晶体复用技术的同步实验演示。
J Synchrotron Radiat. 2015 May;22(3):626-33. doi: 10.1107/S1600577515003999. Epub 2015 Apr 10.
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The Coherent X-ray Imaging instrument at the Linac Coherent Light Source.直线加速器相干光源处的相干X射线成像仪器。
J Synchrotron Radiat. 2015 May;22(3):514-9. doi: 10.1107/S160057751500449X. Epub 2015 Apr 15.
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The X-ray Pump-Probe instrument at the Linac Coherent Light Source.直线加速器相干光源处的X射线泵浦-探测仪。
J Synchrotron Radiat. 2015 May;22(3):503-7. doi: 10.1107/S1600577515005135. Epub 2015 Apr 21.
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The Linac Coherent Light Source.直线加速器相干光源
J Synchrotron Radiat. 2015 May;22(3):472-6. doi: 10.1107/S1600577515005196. Epub 2015 Apr 21.
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Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.通过串联飞秒晶体学揭示的血管紧张素受体结构。
Cell. 2015 May 7;161(4):833-44. doi: 10.1016/j.cell.2015.04.011. Epub 2015 Apr 23.
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Serial femtosecond crystallography: the first five years.连续飞秒晶体学：前五年。
IUCrJ. 2015 Feb 3;2(Pt 2):246-55. doi: 10.1107/S205225251402702X. eCollection 2015 Mar 1.
10
Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array.微流控阱阵列中蛋白质微晶的捕获及X射线衍射研究
Acta Crystallogr D Biol Crystallogr. 2015 Apr;71(Pt 4):928-40. doi: 10.1107/S1399004715002308. Epub 2015 Mar 27.
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