Richmond Neil
Department of Medical Physics, The James Cook University Hospital, Marton Road, Middlesbrough TS4 3BW, UK.
Rep Pract Oncol Radiother. 2017 Sep-Oct;22(5):354-359. doi: 10.1016/j.rpor.2017.06.004. Epub 2017 Jul 22.
This work assesses the dosimetric accuracy of three commercial treatment planning system (TPS) photon dose calculation algorithms in the presence of brass mesh used as a bolus.
Bolus material is used in radiotherapy to provide dose build-up where superficial tissues require irradiation. They are generally water equivalent but high density materials can also be used.
Dose calculations were performed on Monaco and Masterplan TPS (Elekta AB, Sweden) using phantoms defined by the three DICOM CT image sets of water equivalent blocks (no bolus, 1 layer and 2 layers of brass mesh) exported from the CT scanner. The effect of the mesh on monitor units, build-up dose, phantom exit dose and beam penumbra were compared to measured data.
Dose calculations for 6 and 15 MV photon beams on plain water equivalent phantoms were seen to agree well with measurement validating the basic planning system algorithms and models. Dose in the build-up region, phantom exit dose and beam penumbra were poorly modelled in the presence of the brass mesh. The beam attenuation created by the bolus material was overestimated by all three calculation algorithms, at both photon energies, e.g. 1.6% for one layer and up to 3.1% for two layers at 6 MV. The poor modelling of the physical situation in the build-up region is in part a consequence of the high HU artefact caused by the mesh in the CT image.
CT imaging is not recommended with the brass mesh bolus in situ due to the poor accuracy of the subsequent TPS modelling.
本研究评估三种商用治疗计划系统(TPS)光子剂量计算算法在使用黄铜网作为等效填充物时的剂量计算准确性。
等效填充物材料用于放射治疗,在浅表组织需要照射时提供剂量积累。它们通常等效于水,但也可使用高密度材料。
使用从CT扫描仪导出的三个水等效模体(无等效填充物、1层和2层黄铜网)的DICOM CT图像集所定义的模体,在Monaco和Masterplan TPS(瑞典医科达公司)上进行剂量计算。将网格对监测单位、剂量积累、模体出射剂量和射束半值宽度的影响与测量数据进行比较。
在普通水等效模体上对6和15 MV光子束进行的剂量计算与测量结果吻合良好,验证了基本治疗计划系统算法和模型。在存在黄铜网的情况下,剂量积累区域的剂量、模体出射剂量和射束半值宽度的建模效果较差。在两种光子能量下,所有三种计算算法均高估了等效填充物材料产生的射束衰减,例如在6 MV时,一层为1.6%,两层高达3.1%。剂量积累区域物理情况建模不佳部分是由于CT图像中网格导致的高HU伪影。
由于后续TPS建模准确性较差,不建议在黄铜网等效填充物在位的情况下进行CT成像。