Division of General Internal Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Division of Nephrology, Duke University School of Medicine, Durham, North Carolina, USA.
Kidney Int. 2017 Sep;92(3):548-550. doi: 10.1016/j.kint.2017.04.043.
Epidemiologic studies have yielded conflicting results regarding the role of heavy metal exposure in recent epidemics of chronic kidney disease (CKD). In this issue of Kidney International, Tsai et al. examined the combined effects of chromium, lead, and cadmium on kidney function using data from the Nutrition and Health Survey in Taiwan. We add this report to our growing understanding of contemporary epidemics of CKD and highlight considerations for exposure analysis in CKD epidemiologic studies.
流行病学研究对于重金属暴露在近期慢性肾脏病(CKD)流行中的作用得出了相互矛盾的结果。在本期《国际肾脏》杂志中,Tsai 等人利用来自台湾营养与健康调查的数据,研究了铬、铅和镉对肾功能的综合影响。我们将这一报告纳入对当代 CKD 流行的不断深入了解之中,并强调了 CKD 流行病学研究中暴露分析的注意事项。