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中国太原居民的维生素 D 状况及影响因素。

Vitamin D Status of Residents in Taiyuan, China and Influencing Factors.

机构信息

Shanxi University of Traditional Chinese Medicine, 121, Daxue Street, Higher Education Park, Taiyuan 030619, Shanxi, China.

Massey Institute of Food Science and Technology, School of Food and Nutrition, Massey University, Private Bag 11222, Palmerston North 4442, New Zealand.

出版信息

Nutrients. 2017 Aug 18;9(8):898. doi: 10.3390/nu9080898.

Abstract

High prevalence of vitamin D deficiency has been reported worldwide. Residents of Taiyuan, China, were predicted to be at high risk of vitamin D deficiency due to its high latitude, heavy air pollution, and cultural sun avoidance. This study investigated the vitamin D status of office workers, and explored the potential determinants of capillary 25-hydroxyvitamin D (25(OH)D) concentration as well as the relationship between 25(OH)D and metabolic syndrome. Two hundred participants, aged 20 to 80 years, were recruited. Capillary dried blood spot (DBS) 25(OH)D was measured; together with anthropometric (height, weight, and waist circumference), biochemical (serum lipid profile and fasting glucose) measures and a lifestyle questionnaire. Thirty-four percent of participants had 25(OH)D concentrations below 30 nmol/L, indicating deficient vitamin D status. Women's 25(OH)D (median; 32.7 nmol/L (upper and lower quartile; 25.8, 43.8)) was significantly lower than men (44.0 nmol/L (32.3, 55.4)) ( < 0.01). Female gender, higher fasting glucose, and increased smoking ( < 0.05) were negatively associated with 25(OH)D concentration. However, there was no association found between metabolic syndrome (MetS) and 25(OH)D concentration and no significant difference in vitamin D status between men or women with MetS compared to healthy individuals. Vitamin D deficiency was common in urban residents of Taiyuan in winter and more so in women than men.

摘要

维生素 D 缺乏症在全球范围内的患病率很高。由于纬度高、空气污染严重以及文化上避免日晒等原因,中国太原的居民被预测存在维生素 D 缺乏的高风险。本研究调查了上班族的维生素 D 状况,并探讨了毛细血管 25-羟维生素 D(25(OH)D)浓度的潜在决定因素,以及 25(OH)D 与代谢综合征之间的关系。共招募了 200 名年龄在 20 至 80 岁的参与者。测量毛细血管干血斑(DBS)25(OH)D;同时测量人体测量学(身高、体重和腰围)、生化(血脂谱和空腹血糖)指标以及生活方式问卷。34%的参与者 25(OH)D 浓度低于 30 nmol/L,表明存在维生素 D 缺乏症。女性 25(OH)D(中位数;32.7 nmol/L(上下四分位数;25.8、43.8))明显低于男性(44.0 nmol/L(32.3、55.4))(<0.01)。女性性别、较高的空腹血糖和增加的吸烟量(<0.05)与 25(OH)D 浓度呈负相关。然而,代谢综合征(MetS)与 25(OH)D 浓度之间没有关联,而且患有 MetS 的男性或女性与健康个体之间的维生素 D 状态没有显著差异。冬季太原市城镇居民普遍存在维生素 D 缺乏症,女性比男性更为常见。

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