Chen Jing, Yun Chunfeng, He Yuna, Piao Jianhua, Yang Lichen, Yang Xiaoguang
Department of Trace Element Nutrition, National Institute of Nutrition and Health, Chinese Center for Disease Control and Prevention, Room 103, Nanwei Road No. 29, Xicheng District, Beijing, 100050, People's Republic of China.
Institute of Population Research, Peking University, Beijing, 100871, People's Republic of China.
Nutr J. 2017 Jan 14;16(1):3. doi: 10.1186/s12937-016-0224-3.
Vitamin D inadequacy is common among the elderly, especially within the Asian population. The vitamin D status among healthy adults in the elderly Chinese population was evaluated.
A total of 6014 healthy adults aged 60 years or older (2948 men, 3066 women) participated in this descriptive cross-sectional analysis. Possible predictors of vitamin D inadequacy were evaluated via multiple logistic regression analyses.
The median serum 25-hydroxyvitamin D (25(OH)D) levels were 61.0 nmol/l (interquartile range (IQR) 44.3-80.6, range 5.1-154.5) for men and 53.7 nmol/l (IQR 38.8-71.0, range 6.0-190.0) for women, with 34.1% (95% confidence interval (CI) 32.4-35.8) of men and 44.0% (95% CI 42.2-45.8) of women presenting vitamin D inadequacy (25(OH)D <50 nmol/l). According to the multivariate logistic regression analyses, vitamin D inadequacy was positively correlated with female gender (P <0.0001), underweight (P = 0.0259), the spring season (P <0.0001), low ambient UVB levels (P <0.0001) and living in large cities (P = 0.0026). For men, vitamin D inadequacy was positively correlated with the spring season (P = 0.0015), low ambient UVB levels (P <0.0001) and living in large cities (P = 0.0022); for women, vitamin D inadequacy was positively correlated with the spring season (P = 0.0005) and low ambient UVB levels (P <.0001).
Vitamin D inadequacy is prevalent among the elderly population in China. Because residing in regions with low ambient UVB levels increases the risk of vitamin D inadequacy both for men and women, vitamin D supplementation and sensible sun exposure should be encouraged, especially during the cooler seasons. Further studies are required to determine the optimal vitamin D intake and sun exposure levels to maintain sufficient vitamin D levels in the elderly Chinese population.
维生素D缺乏在老年人中很常见,尤其是在亚洲人群中。本研究评估了中国老年健康成年人的维生素D状况。
共有6014名60岁及以上的健康成年人(2948名男性,3066名女性)参与了这项描述性横断面分析。通过多元逻辑回归分析评估维生素D缺乏的可能预测因素。
男性血清25-羟基维生素D(25(OH)D)水平中位数为61.0nmol/l(四分位数间距(IQR)44.3 - 80.6,范围5.1 - 154.5),女性为53.7nmol/l(IQR 38.8 - 71.0,范围6.0 - 190.0),34.1%(95%置信区间(CI)32.4 - 35.8)的男性和44.0%(95%CI 42.2 - 45.8)的女性存在维生素D缺乏(25(OH)D<50nmol/l)。根据多元逻辑回归分析,维生素D缺乏与女性性别(P<0.0001)、体重过轻(P = 0.0259)、春季(P<0.0001)、环境中低水平紫外线B(UVB)(P<0.0001)以及居住在大城市(P = 0.0026)呈正相关。对于男性,维生素D缺乏与春季(P = 0.0015)、环境中低水平UVB(P<0.0001)以及居住在大城市(P = 0.0022)呈正相关;对于女性,维生素D缺乏与春季(P = 0.0005)和环境中低水平UVB(P<0.0001)呈正相关。
维生素D缺乏在中国老年人群中普遍存在。由于居住在环境中UVB水平较低的地区会增加男性和女性维生素D缺乏的风险,因此应鼓励补充维生素D并进行合理的阳光照射,尤其是在较凉爽季节。需要进一步研究以确定中国老年人群维持充足维生素D水平的最佳维生素D摄入量和阳光照射水平。