昼夜光照对昼夜节律的破坏。
Disruption of Circadian Rhythms by Light During Day and Night.
作者信息
Figueiro Mariana G
机构信息
Lighting Research Center, Rensselaer Polytechnic Institute, Troy, NY, 12180,
出版信息
Curr Sleep Med Rep. 2017 Jun;3(2):76-84. doi: 10.1007/s40675-017-0069-0.
Abstract
PURPOSE OF REVIEW
This study aims to discuss possible reasons why research to date has not forged direct links between light at night, acute melatonin suppression or circadian disruption, and risks for disease.
RECENT FINDINGS
Data suggest that irregular light-dark patterns or light exposures at the wrong circadian time can lead to circadian disruption and disease risks. However, there remains an urgent need to: (1) specify light stimulus in terms of circadian rather than visual response; (2) when translating research from animals to humans, consider species-specific spectral and absolute sensitivities to light; (3) relate the characteristics of photometric measurement of light at night to the operational characteristics of the circadian system; and (4) examine how humans may be experiencing too little daytime light, not just too much light at night.
SUMMARY
To understand the health effects of light-induced circadian disruption, we need to measure and control light stimulus during the day and at night.
摘要
综述目的
本研究旨在探讨为何迄今为止的研究尚未在夜间光照、褪黑素急性抑制或昼夜节律紊乱与疾病风险之间建立直接联系。
最新发现
数据表明，不规则的明暗模式或在错误的昼夜节律时间进行光照暴露会导致昼夜节律紊乱和疾病风险。然而，仍迫切需要：（1）根据昼夜节律而非视觉反应来明确光刺激；（2）在将动物研究转化为人体研究时，考虑物种对光的特定光谱和绝对敏感度；（3）将夜间光的光度测量特征与昼夜节律系统的运行特征联系起来；（4）研究人类可能不仅夜间光照过多，白天光照也过少的情况。
总结
为了解光诱导的昼夜节律紊乱对健康的影响，我们需要在白天和夜间测量并控制光刺激。
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