Bender Bruce G, Depew Ann, Emmett Amanda, Goelz Kelly, Make Barry, Sharma Sanjay, Underwood Jennifer, Stempel David
Departments of Pediatrics, National Jewish Health, Denver, Colorado.
Department of Medicine, National Jewish Health, Denver, Colorado.
Chronic Obstr Pulm Dis. 2016 Oct 7;3(4):769-777. doi: 10.15326/jcopdf.3.4.2016.0142.
Pulmonary rehabilitation programs improve dyspnea and health status associated with chronic obstructive pulmonary disease (COPD), but benefits wane when patients return to a sedentary lifestyle. This study tested a simple, low-resource, low-cost home walking program. In this single center, 3-month study, 115 COPD patients were randomized to a control cohort or a goal setting cohort. Each patient met with study staff and received 5 telephone calls at 2-week intervals. During these contacts, the Goal group was assisted by a wellness coach who helped them set personal activity goals. All patients wore a pedometer to record daily steps, the primary study outcome. Over the 12-week interval, the average step-per-days was 36% higher for the Goal cohort patients (Week 12 mean = 4390) than for Control patients (mean = 3790). No group differences emerged on the modified Medical Research Council (mMRC) dyspnea scale, the COPD Assessment Test, or the St. George's Respiratory Questionnaire. Secondary analyses indicated that even patients with greater disease severity, including those with an mMRC score >2 or forced expiratory volume in 1 second (FEV) % predicted below 50%, increased their walking relative to Control patients. Almost half (48%) of Goal patients successfully reached at least one personal goal such as increasing stamina and activity, or decreasing shortness of breath or weight. A relatively low-resource wellness coaching, goal-setting intervention resulted in a small improvement in the activity level of COPD patients over a 12-week period including those with marked pulmonary impairment. Further investigation should be directed at understanding the optimal blend of in person and remote coaching needed to produce the greatest cost-to-benefit ratio.
肺康复计划可改善与慢性阻塞性肺疾病(COPD)相关的呼吸困难和健康状况,但患者恢复久坐生活方式后,益处就会减弱。本研究测试了一项简单、资源需求低、成本低的家庭步行计划。在这项单中心、为期3个月的研究中,115名COPD患者被随机分为对照组或目标设定组。每位患者与研究人员会面,并每隔2周接到5次电话。在这些联系过程中,目标组得到了一名健康教练的协助,教练帮助他们设定个人活动目标。所有患者都佩戴计步器来记录每日步数,这是主要的研究结果。在12周的时间里,目标组患者的日均步数(第12周平均值 = 4390步)比对照组患者(平均值 = 3790步)高36%。在改良医学研究委员会(mMRC)呼吸困难量表、慢性阻塞性肺疾病评估测试或圣乔治呼吸问卷上,两组没有差异。二次分析表明,即使是病情更严重的患者,包括mMRC评分>2或1秒用力呼气量(FEV)%预计低于50%的患者,相对于对照组患者,他们的步行量也有所增加。几乎一半(48%)的目标组患者成功实现了至少一个个人目标,如增强耐力和活动能力、减轻呼吸急促或体重。一项资源相对较少的健康指导、目标设定干预措施,在12周内使COPD患者的活动水平有了小幅提高,包括那些有明显肺功能损害的患者。应进一步开展研究,以了解为实现最大成本效益比所需的面对面指导和远程指导的最佳组合。