GPR133 Promotes Glioblastoma Growth in Hypoxia.
作者信息
Frenster Joshua D, Inocencio Julio F, Xu Zhongye, Dhaliwal Joravar, Alghamdi Abdulhakeem, Zagzag David, Bayin N Sumru, Placantonakis Dimitris G
机构信息
Department of Neurosurgery, NYU School of Medicine, New York, New York.
Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, New York.
出版信息
Neurosurgery. 2017 Sep 1;64(CN_suppl_1):177-181. doi: 10.1093/neuros/nyx227.
Abstract
摘要
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本文引用的文献
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GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth.GPR133（ADGRD1）是一种粘附性G蛋白偶联受体，对胶质母细胞瘤的生长至关重要。
Oncogenesis. 2016 Oct 24;5(10):e263. doi: 10.1038/oncsis.2016.63.
2
Adhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms.黏附G蛋白偶联受体：从体外药理学到体内机制
Mol Pharmacol. 2015 Sep;88(3):617-23. doi: 10.1124/mol.115.098749. Epub 2015 May 8.
3
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells.Sox2拮抗Hippo信号通路以维持癌细胞的干性。
Nat Commun. 2015 Apr 2;6:6411. doi: 10.1038/ncomms7411.
4
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Pharmacol Rev. 2015;67(2):338-67. doi: 10.1124/pr.114.009647.
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PLoS One. 2014 Dec 26;9(12):e116114. doi: 10.1371/journal.pone.0116114. eCollection 2014.
6
A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133.胞外域内的一种拴系激动剂可激活粘附性G蛋白偶联受体GPR126和GPR133。
Cell Rep. 2014 Dec 24;9(6):2018-26. doi: 10.1016/j.celrep.2014.11.036. Epub 2014 Dec 18.
7
Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia.抗血管生成策略再探讨：从饿死肿瘤到缓解缺氧
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8
Glioblastoma stem cells: Molecular characteristics and therapeutic implications.胶质母细胞瘤干细胞：分子特征与治疗意义
World J Stem Cells. 2014 Apr 26;6(2):230-8. doi: 10.4252/wjsc.v6.i2.230.
9
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10
Exploring TCGA Pan-Cancer data at the UCSC Cancer Genomics Browser.探索 UCSC 癌症基因组浏览器中的 TCGA 泛癌症数据。
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